Beta-Bromostyrene (CAS 103-64-0) is a chemical compound of significant interest across various industries, primarily valued for its role as an intermediate in organic synthesis and its applications in pharmaceutical development. Understanding its properties and procurement channels is vital for scientists, chemists, and procurement specialists alike.

Physical and Chemical Properties:

Beta-Bromostyrene is typically described as a clear, yellowish to brown liquid. It possesses a molecular formula of C8H7Br and a molecular weight of approximately 183.05 g/mol. Key physical properties include a melting point around 7°C and a boiling point of approximately 219-221°C at atmospheric pressure, though often distilled at reduced pressure (e.g., 110-112°C at 20 mmHg). Its density is around 1.427 g/mL at 25°C, and it exhibits a refractive index (n20/D) of 1.608. The compound is soluble in common organic solvents like alcohol but has limited solubility in water.

The chemical structure of beta-Bromostyrene features a phenyl group attached to a vinyl group that carries a bromine atom on the beta-carbon. This structure makes it a reactive molecule, amenable to various chemical transformations, including addition reactions across the double bond and substitution or elimination reactions involving the bromine atom. It exists as a mixture of cis and trans isomers.

Key Applications:

The primary utility of beta-Bromostyrene lies in its role as a building block in organic synthesis. It is extensively used:

  • As an intermediate for the synthesis of pharmaceuticals, contributing to the development of new drug molecules.
  • In the agrochemical industry for the creation of crop protection agents and intermediates.
  • In material science for developing specialized polymers and functional materials.
  • As a versatile reagent in academic and industrial research labs for exploring novel chemical reactions and pathways.

Its reactive nature allows for participation in important synthetic reactions such as Heck, Suzuki, and other cross-coupling reactions, enabling the construction of diverse and complex organic structures.

Procurement Considerations:

When looking to buy beta-Bromostyrene, especially for commercial or research purposes, several factors are important for ensuring product quality and a reliable supply. Firstly, the purity of the compound is critical. Manufacturers often specify purity levels, typically around 97-98%, with analytical data like GC-MS or NMR available to confirm identity and purity.

Secondly, establishing a relationship with a reputable manufacturer and supplier is key. Companies offering beta-Bromostyrene often provide detailed product specifications, safety data sheets (SDS), and Certificates of Analysis (CoA). Sourcing from established chemical suppliers, particularly those based in China, can offer competitive pricing and a robust supply chain. NINGBO INNO PHARMCHEM CO.,LTD. is an example of a manufacturer dedicated to providing high-quality fine chemicals for global markets.

In summary, beta-Bromostyrene (CAS 103-64-0) is a valuable chemical intermediate. By understanding its properties and prioritizing reliable sourcing from qualified manufacturers and suppliers, researchers and manufacturers can effectively leverage its potential in their synthetic endeavors.