In the realm of biochemistry and molecular biology, understanding the fundamental roles of key biomolecules is crucial. N-Acetyl-D-Glucosamine (NAG), a derivative of glucose with the CAS number 7512-17-6, is one such molecule, playing indispensable roles in a variety of biological systems. For researchers and academic institutions, sourcing high-purity NAG is essential for accurate experimental outcomes.

NAG as a Fundamental Building Block:
N-Acetyl-D-Glucosamine is a monosaccharide unit that forms the backbone of many complex biopolymers. Its significance is underscored by its presence in:

  • Chitin: NAG is the monomeric unit of chitin, a structural polysaccharide found in the exoskeletons of arthropods (like crustaceans and insects) and the cell walls of fungi. This makes NAG indispensable for researchers studying these organisms or exploring novel biomaterials derived from chitin.
  • Glycosaminoglycans (GAGs): NAG is a crucial precursor for synthesizing various GAGs, including hyaluronic acid, heparan sulfate, and keratan sulfate. These GAGs are vital components of the extracellular matrix, playing roles in cell signaling, tissue hydration, lubrication, and structural support.
  • Glycoproteins and Glycolipids: NAG is commonly found in the carbohydrate chains of glycoproteins and glycolipids, which are involved in cell-cell recognition, immune responses, and protein folding.

Biochemical and Physiological Functions:
Beyond its structural roles, NAG is implicated in several physiological processes:

  • O-GlcNAcylation: The post-translational modification of proteins with a single NAG moiety (O-GlcNAcylation) is a dynamic process that influences protein function, gene expression, and cellular signaling pathways, often competing with phosphorylation.
  • Immune Modulation: Studies suggest that NAG can influence immune responses, potentially by modulating inflammatory pathways and supporting the gut microbiome.
  • Cell Signaling: As a component of complex glycans, NAG is involved in various cell-to-cell interactions and signaling cascades.

Where to Buy High-Quality NAG:
For precise biochemical research, obtaining N-Acetyl-D-Glucosamine with guaranteed purity is paramount. As a reliable chemical supplier, we offer high-purity NAG (CAS 7512-17-6) suitable for demanding laboratory applications. We understand the needs of researchers and provide consistent quality, facilitating breakthroughs in various biological studies. When you need to buy N-Acetyl-D-Glucosamine for your research, trust our commitment to purity and timely delivery.

For scientific institutions and researchers, ensuring the quality of biochemical reagents is non-negotiable. As a reputable N-Acetyl-D-Glucosamine supplier, we are equipped to meet your needs.