In the realm of fine chemical synthesis and organic chemistry, access to high-quality, specialized building blocks is essential for innovation. Boc-D-2-Chloro-Phenylalanine (CAS: 80102-23-4) stands out as a particularly valuable intermediate for chemists engaged in complex synthesis projects. This article explores its applications and why sourcing it from a trusted manufacturer is crucial for success.

What Makes Boc-D-2-Chloro-Phenylalanine Unique?

Boc-D-2-Chloro-Phenylalanine is an unnatural amino acid derivative characterized by three key features:

  1. Boc Protection: The tert-butyloxycarbonyl (Boc) group protects the amine functionality. This is critical for controlled reactions in multi-step synthesis, particularly in peptide synthesis, by preventing unwanted side reactions.
  2. D-Chirality: The 'D' designation refers to the stereochemistry of the alpha-carbon. Incorporating D-amino acids into peptides can confer unique properties like resistance to enzymatic degradation, which is highly advantageous in pharmaceutical applications.
  3. Ortho-Chlorination: The chlorine atom at the 2-position of the phenyl ring introduces specific steric and electronic effects. This modification can alter the compound's reactivity, its conformation, and its interactions with biological targets or other molecules in synthesis.

These attributes make Boc-D-2-Chloro-Phenylalanine a versatile tool for chemists aiming to create novel molecules with specific properties.

Applications in Chemical Synthesis

The primary applications of Boc-D-2-Chloro-Phenylalanine revolve around its use as a sophisticated building block:

  • Peptide Synthesis: As a protected D-amino acid, it is directly used in solid-phase or solution-phase peptide synthesis to introduce specific structural modifications, enhancing peptide stability or altering receptor binding. Researchers often look for Boc-D-2-Chloro-Phenylalanine price information to budget for their synthesis projects.
  • Medicinal Chemistry: Chemists utilize this compound to synthesize potential drug candidates. The chlorine substituent and D-configuration can be key to achieving desired pharmacokinetic or pharmacodynamic profiles.
  • Ligand Design: In coordination chemistry or the design of catalysts, specialized amino acid derivatives can serve as chiral ligands, influencing the outcome of enantioselective reactions.
  • Custom Synthesis Projects: For specific research needs, this compound can be a starting point for further chemical modifications, making it invaluable for bespoke synthesis services.

For effective advanced chemical synthesis, sourcing from a reliable Boc-D-2-Chloro-Phenylalanine supplier is paramount. A trusted Boc-D-2-Chloro-Phenylalanine manufacturer in China can provide the necessary quality and scale. NINGBO INNO PHARMCHEM CO.,LTD. offers high-purity Boc-D-2-Chloro-Phenylalanine, ensuring your synthesis projects proceed smoothly.

When you need to buy Boc-D-2-Chloro-Phenylalanine, consider the benefits of a direct relationship with a manufacturer. We provide not only quality materials but also the technical support that can be crucial for complex chemical endeavors. Partner with NINGBO INNO PHARMCHEM CO.,LTD. for your advanced synthesis needs.