In the realm of pharmaceutical manufacturing and advanced chemical synthesis, the availability of high-quality intermediates is non-negotiable. Boc-D-4-Iodophenylglycine stands out as a critical chiral building block, indispensable for the creation of a diverse range of therapeutic agents, particularly those involving complex peptide structures or requiring specialized molecular design. Its consistent supply from reputable manufacturers is key for many research and development pipelines.

The chemical structure of Boc-D-4-Iodophenylglycine, featuring both the protective Boc group and a strategically placed iodine atom, makes it exceptionally versatile. The Boc group ensures controlled reactions in peptide synthesis, preventing racemization and ensuring stereochemical integrity. The iodine atom, on the other hand, serves as a valuable synthetic handle. It can be readily substituted or utilized in cross-coupling reactions, such as Suzuki or Heck couplings, to introduce further complexity or functional groups. This makes it an ideal intermediate for designing novel small molecules and peptide-based drugs.

For pharmaceutical companies and contract manufacturing organizations (CMOs), sourcing Boc-D-4-Iodophenylglycine involves a rigorous selection process for suppliers. Key considerations include purity (typically exceeding 97%), stereochemical purity, reliable availability, and competitive pricing. When looking to buy this intermediate, partnering with a manufacturer that adheres to strict quality control standards and can provide comprehensive documentation like Certificates of Analysis (CoA) is paramount. Many leading chemical suppliers based in China are equipped to meet these stringent requirements.

The applications of Boc-D-4-Iodophenylglycine are broad. It's a cornerstone for synthesizing non-natural amino acids incorporated into peptides to enhance their therapeutic profiles, such as increased stability against enzymatic degradation or improved receptor binding. Furthermore, its iodinated phenyl ring makes it a prime candidate for developing radiopharmaceuticals, where the iodine can be isotopically labeled for diagnostic imaging (e.g., SPECT or PET scans) or targeted radiotherapy. This capability positions it as a critical component in the development of advanced cancer therapies and diagnostic tools.

Procuring this specialized chemical efficiently can significantly impact project timelines and costs. Bulk purchase inquiries for Boc-D-4-Iodophenylglycine should be directed to established suppliers who can offer dedicated production capacities and responsive customer support. Understanding the material's specifications, including its CAS number (176199-35-2), and ensuring its compliance with regulatory standards are crucial steps before integration into any manufacturing process. Choosing the right supplier ensures not just the quality of the intermediate but also the reliability of your production output.