Boc-D-Serine (CAS 6368-20-3) is a versatile and critically important chemical intermediate, widely recognized for its applications across several advanced scientific disciplines, most notably in peptide synthesis and pharmaceutical research. As a manufacturer and supplier, we see firsthand the value this compound brings to researchers and developers globally.

The primary application of Boc-D-Serine lies in Peptide Synthesis. As a Boc-protected D-amino acid, it is a fundamental building block in both solid-phase peptide synthesis (SPPS) and solution-phase methods. The tert-butoxycarbonyl (Boc) group serves as a temporary protective shield for the alpha-amino group, preventing unwanted side reactions during the coupling of amino acids. This protection allows for the precise, stepwise assembly of peptide chains with controlled sequences and specific stereochemistry. The D-configuration of serine is particularly sought after for creating peptides with unique conformational properties or enhanced stability against enzymatic degradation.

In the realm of Pharmaceutical Research and Drug Development, Boc-D-Serine acts as a key chiral intermediate. Its structure is incorporated into various therapeutic agents, including peptide-based drugs, small molecule inhibitors, and drugs targeting neurological pathways. The precise stereochemistry of Boc-D-Serine is often critical for the biological activity and specificity of the final drug product. For instance, in the development of treatments for neurological disorders, the D-serine moiety can play a role in modulating neurotransmitter systems. Companies looking to buy Boc-D-Serine for these applications seek high purity and consistent quality to ensure the efficacy and safety of their drug candidates.

Furthermore, Boc-D-Serine finds application in Neuroscience Research. Studies have investigated the role of D-serine in the central nervous system, particularly its involvement as a co-agonist of NMDA receptors, which are crucial for synaptic plasticity, learning, and memory. Researchers use Boc-D-Serine to synthesize analogues or study mechanisms related to these receptors, contributing to the understanding and development of therapies for conditions such as schizophrenia and Alzheimer's disease.

Beyond these core areas, Boc-D-Serine can be utilized in Bioconjugation and other specialized organic synthesis projects where a protected chiral amino acid with a hydroxyl side chain is required. The ability to selectively deprotect or functionalize the hydroxyl group adds to its versatility.

As a trusted manufacturer and supplier of Boc-D-Serine (CAS 6368-20-3), we are dedicated to providing researchers and developers with a reliable source of this high-value chemical intermediate. Our commitment to quality, competitive pricing, and consistent supply ensures that your projects in peptide synthesis, drug development, and neuroscience research can proceed with confidence. Contact us to request a quote and secure your supply of Boc-D-Serine.