Boc-GABA-OH: Your Go-To Building Block for Advanced Peptide Synthesis
Peptide synthesis is a cornerstone of modern biochemical research and pharmaceutical development. The ability to construct complex peptide chains with precise sequences and functionalities is critical for creating new therapeutics, diagnostic tools, and research probes. Within this intricate process, the use of protected amino acid derivatives plays a pivotal role, and Boc-GABA-OH (CAS: 57294-38-9), also known as N-Boc-gamma-aminobutyric acid, stands out as a valuable component for specific peptide architectures.
The tert-butyloxycarbonyl (Boc) group in Boc-GABA-OH acts as a temporary protecting group for the amine functionality of gamma-aminobutyric acid. This protection is essential during solid-phase or solution-phase peptide synthesis, preventing the amine from participating in unwanted side reactions while other parts of the growing peptide chain are modified or coupled. Once the desired synthetic steps are completed, the Boc group can be selectively removed under mild acidic conditions, allowing for further chain extension or deprotection of other functionalities. This controlled protection and deprotection strategy is fundamental to achieving high yields and purities in peptide synthesis.
While gamma-aminobutyric acid itself is an important neurotransmitter, its incorporation into peptide structures requires careful management of its amine group. Boc-GABA-OH provides a convenient and effective solution for researchers who need to incorporate this specific amino acid derivative into their peptide sequences. Its white powder form and high purity ensure reliable performance in various synthesis protocols. For scientists and procurement specialists seeking to buy Boc-GABA-OH, it is imperative to partner with a reputable chemical manufacturer and supplier who can guarantee consistent product quality and availability.
The availability of Boc-GABA-OH from reliable manufacturers in China offers a strategic advantage for global research institutions and pharmaceutical companies. These suppliers are often equipped to handle large-scale production and can offer competitive pricing, making this essential building block more accessible for extensive research projects. Whether you are exploring novel peptide-based drugs, creating specialized biomaterials, or conducting fundamental research in molecular biology, ensuring a steady supply of high-quality Boc-GABA-OH is paramount.
As a versatile amino acid derivative, Boc-GABA-OH contributes significantly to the expansion of synthetic capabilities in peptide chemistry. Its strategic application allows for the creation of more complex and functional peptides. If your research demands precise peptide synthesis and requires a dependable source for this crucial intermediate, consider our capabilities as a leading manufacturer and supplier of Boc-GABA-OH. Reach out to us to discuss your peptide synthesis needs and obtain a quotation.
Perspectives & Insights
Logic Thinker AI
“The tert-butyloxycarbonyl (Boc) group in Boc-GABA-OH acts as a temporary protecting group for the amine functionality of gamma-aminobutyric acid.”
Molecule Spark 2025
“This protection is essential during solid-phase or solution-phase peptide synthesis, preventing the amine from participating in unwanted side reactions while other parts of the growing peptide chain are modified or coupled.”
Alpha Pioneer 01
“Once the desired synthetic steps are completed, the Boc group can be selectively removed under mild acidic conditions, allowing for further chain extension or deprotection of other functionalities.”