For chemical professionals involved in peptide synthesis, pharmaceutical development, or general organic chemistry, understanding the procurement of essential reagents like Boc-Gly-OtBu (Boc-glycine tert-butyl ester), CAS 111652-20-1, is crucial. Key considerations revolve around product purity, competitive pricing, and reliable sourcing. This article explores these aspects, guiding you on how to effectively buy Boc-Gly-OtBu and ensure your synthesis projects are successful.

Understanding the Value of Boc-Gly-OtBu Purity

Boc-Gly-OtBu, a protected form of glycine, is indispensable in applications demanding precision. Its primary use is in peptide synthesis, where impurities can lead to truncated peptides, incorrect sequences, or reduced coupling efficiencies, significantly impacting research outcomes and product quality. Therefore, high purity, typically stated as ≥99% by manufacturers, is a non-negotiable characteristic. This level of purity ensures that the Boc-protected glycine moiety is cleanly incorporated into the target molecule without introducing unwanted side reactions or contaminants. As a white crystal powder, its physical form also lends itself to accurate measurement and handling.

Factors Influencing Boc-Gly-OtBu Price

The price of Boc-Gly-OtBu CAS 111652-20-1 is influenced by several market dynamics:

  • Raw Material Costs: Fluctuations in the cost of precursor chemicals can impact the final product price.
  • Manufacturing Scale: Larger production volumes often lead to economies of scale, potentially reducing the per-unit cost.
  • Purity Levels: Higher purity grades, such as ≥99%, naturally command higher prices due to the additional purification steps involved.
  • Supplier Reputation and Location: Established suppliers, particularly those in regions with robust chemical manufacturing infrastructure like China, can often offer competitive pricing while maintaining quality.
  • Market Demand: Increased demand from the peptide synthesis and pharmaceutical sectors can also influence pricing.

Strategic Procurement: Buying Boc-Gly-OtBu Effectively

To secure the best value when you need to buy Boc-Gly-OtBu CAS 111652-20-1, consider the following:

  • Identify Reputable Manufacturers: Partner with established chemical manufacturers who specialize in amino acid derivatives and intermediates. Companies like NINGBO INNO PHARMCHEM CO.,LTD. have a proven track record.
  • Request Quotes: Obtain detailed quotes from multiple suppliers, comparing not only price but also purity specifications, packaging options (e.g., 25kg/drum), and delivery terms.
  • Verify Quality: Always request a Certificate of Analysis (CoA) for each batch to confirm purity and adherence to specifications.
  • Consider Bulk Purchases: For ongoing projects or larger requirements, bulk orders often present significant cost savings.

By focusing on these procurement strategies, researchers and manufacturers can efficiently source high-quality Boc-Gly-OtBu, ensuring the success of their synthesis endeavors. Reliable sourcing from Chinese manufacturers offers a practical pathway to obtain this vital chemical intermediate at competitive prices.