For chemists and researchers engaged in complex organic synthesis, a thorough understanding of the properties of key building blocks is indispensable. Boc-L-homophenylalanine (CAS: 100564-78-1) is one such compound, serving as a versatile amino acid derivative with significant utility in various chemical applications, particularly within the pharmaceutical industry. This article explores its fundamental chemical properties and outlines its principal uses, offering valuable insights for those looking to purchase this compound.

Boc-L-homophenylalanine is characterized by its molecular formula C15H21NO4 and a molecular weight of approximately 279.33 g/mol. It typically presents as a white powder, a physical form that facilitates handling and measurement in laboratory settings. A key physical property is its melting point, which generally falls within the range of 76-80°C. This characteristic is important for identifying the compound and assessing its purity. The compound's solubility profile, while not always explicitly detailed in basic datasheets, is generally understood to be compatible with common organic solvents used in synthesis, such as dichloromethane, ethyl acetate, and alcohols, while exhibiting limited solubility in water.

The chemical functionality of Boc-L-homophenylalanine lies in its protected alpha-amino group and its carboxylic acid moiety, along with the characteristic side chain of homophenylalanine. The Boc protecting group is readily cleaved under acidic conditions (e.g., using trifluoroacetic acid), regenerating the free amine for further reactions. This selective protection and deprotection strategy is the cornerstone of its utility in peptide synthesis, allowing for controlled chain elongation. As a chemical intermediate, its structure can also be modified or incorporated into larger molecular frameworks through various coupling reactions.

The applications of Boc-L-homophenylalanine are diverse, primarily revolving around its role as a chiral building block. In peptide synthesis, it enables the incorporation of a non-natural amino acid with a specific side chain structure, which can influence the peptide's biological activity, stability, or interaction with target molecules. This makes it a sought-after reagent for researchers developing novel therapeutics, diagnostic agents, or specialized peptides for research purposes. For those intending to buy, understanding these applications helps in determining the required purity and quantity.

Beyond peptide chemistry, Boc-L-homophenylalanine can be a valuable starting material or intermediate in the synthesis of other organic molecules, including potential pharmaceutical candidates. Its inherent chirality and functional groups provide a platform for creating complex structures with defined stereochemistry. Manufacturers and suppliers play a crucial role in ensuring that this compound is available in consistent quality and quantity. When you are ready to purchase, seeking out a reliable supplier in China can offer both cost advantages and assured product specifications.

In summary, Boc-L-homophenylalanine is a well-defined chemical entity with critical applications in synthetic chemistry. Its physical and chemical properties, particularly its protected amino group and its role as a chiral building block, make it an essential compound for advanced research. If your work requires this versatile intermediate, consider reaching out to reputable manufacturers to discuss your purchasing needs.