While Boc-Lys(Boc)-ONp (CAS: 2592-19-0) is most widely recognized for its indispensable role in peptide synthesis, its utility extends far beyond basic amino acid coupling. As a versatile and precisely engineered chemical intermediate, this protected lysine derivative is a valuable asset in various advanced scientific and industrial applications. For researchers and developers looking to buy high-quality Boc-Lys(Boc)-ONp, NINGBO INNO PHARMCHEM CO.,LTD. stands as a premier manufacturer and supplier in China, offering purity and reliability.

Expanding the Horizons of Boc-Lys(Boc)-ONp Use:

The unique structure of Boc-Lys(Boc)-ONp, featuring dual Boc protection on its amino groups and an activated p-nitrophenyl ester, makes it an excellent starting material for a range of sophisticated chemical manipulations:

  • Advanced Peptide Synthesis: Beyond simple linear peptides, Boc-Lys(Boc)-ONp is crucial for synthesizing branched peptides, cyclic peptides, and peptides with complex modifications. The ability to selectively deprotect and functionalize the epsilon-amino group allows for the creation of custom peptide architectures with tailored properties.
  • Drug Delivery Systems: Lysine residues are often incorporated into drug delivery vehicles, such as peptide-drug conjugates (PDCs) or polymeric nanoparticles. The epsilon-amino group can serve as a conjugation point for attaching therapeutic agents, targeting ligands, or imaging agents. Boc-Lys(Boc)-ONp provides a clean and efficient way to introduce these lysine moieties with controlled attachment sites.
  • Bioconjugation Chemistry: The field of bioconjugation relies on robust methods for linking biomolecules. Boc-Lys(Boc)-ONp is used to prepare lysine-functionalized peptides or other biomolecules that can then be reacted with activated molecules (e.g., fluorophores, antibodies, surfaces). The specific reactivity of the p-nitrophenyl ester and the protected amino groups allows for controlled conjugation chemistries.
  • Development of Peptidomimetics: Peptidomimetics are compounds that mimic the biological activity of peptides but possess enhanced stability, bioavailability, or altered pharmacological properties. Boc-Lys(Boc)-ONp can be used in the synthesis of these complex molecules, incorporating the structural and functional features of lysine into non-peptide frameworks.
  • Surface Functionalization: In materials science and diagnostics, surfaces can be functionalized with peptides or amino acids to impart specific biological recognition properties or to create platforms for sensing. Boc-Lys(Boc)-ONp can be used to create lysine-terminated sequences that are then immobilized onto surfaces, such as biosensors or microarrays.
  • Research in Protein Modification: Understanding post-translational modifications of lysine residues in proteins (e.g., acetylation, ubiquitination) is vital. Synthetic peptides containing specific modifications, often requiring protected lysine intermediates like Boc-Lys(Boc)-ONp, are used as model substrates or for studying enzymatic activity.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting these advanced applications by ensuring a consistent supply of high-purity Boc-Lys(Boc)-ONp. Our stringent quality control, competitive price, and reliable supply chain make us an ideal partner for your research and development needs. We encourage scientists and procurement specialists to purchase or order this versatile intermediate from us. Contact us today for a quotation and to explore how our high-quality Boc-Lys(Boc)-ONp can advance your next project.