Boc-Orn-OH: Your Key Intermediate for Advanced Peptide Synthesis
In the intricate world of peptide synthesis, having access to high-purity, reliable building blocks is paramount. One such crucial intermediate is Boc-Orn-OH, or N-alpha-Boc-L-ornithine. For researchers and procurement managers in the pharmaceutical and biotechnology sectors, understanding its role and how to source it effectively can significantly impact project success. This article delves into the significance of Boc-Orn-OH and highlights the benefits of partnering with a trusted manufacturer and supplier.
What is Boc-Orn-OH?
Boc-Orn-OH is a derivative of the amino acid ornithine. The 'Boc' (tert-butyloxycarbonyl) group serves as a protecting group for the alpha-amino function, a standard practice in peptide synthesis to control the reaction process. L-ornithine itself is a non-proteinogenic amino acid, often found in urea cycle intermediates and collagen. Its incorporation into peptides can impart unique structural and functional properties, making it valuable in designing peptidomimetics, therapeutic peptides, and complex biochemical tools.
Why is Boc-Orn-OH Essential for Peptide Synthesis?
The primary utility of Boc-Orn-OH lies in its role in solid-phase peptide synthesis (SPPS). In SPPS, amino acids are sequentially added to a growing peptide chain anchored to a solid support. The Boc protecting group on Boc-Orn-OH allows for selective deprotection and coupling reactions, ensuring that the ornithine residue is incorporated precisely where needed without unwanted side reactions. Its chemical formula is C10H20N2O4, with a molecular weight of approximately 232.3 g/mol. This precise chemical definition is critical for achieving high purity in the final peptide product.
Applications Beyond Standard Peptide Synthesis
While its main application is in peptide synthesis, Boc-Orn-OH also serves as a vital intermediate in various organic synthesis pathways. Pharmaceutical companies utilize it in the R&D phases for developing new drug candidates. Its specific structure makes it a valuable component for medicinal chemists exploring novel molecular architectures. As a reliable chemical intermediate, it contributes to the advancement of therapeutic discovery.
Sourcing High-Quality Boc-Orn-OH: Manufacturer vs. Supplier
When looking to buy Boc-Orn-OH, discerning the difference between a manufacturer and a supplier is crucial. A manufacturer, like NINGBO INNO PHARMCHEM CO.,LTD., has direct control over the production process, ensuring stringent quality control from raw materials to the final product. This often translates to higher purity and consistency, which is non-negotiable in scientific research. Partnering with a direct manufacturer allows for better pricing, particularly for bulk quantities, and ensures a more stable supply chain.
As a leading Boc-Orn-OH supplier in China, we are dedicated to providing researchers worldwide with access to this essential compound. We understand the importance of reliable sourcing for your projects, whether you need small quantities for initial research or larger volumes for production. Our commitment to quality means you receive a product that meets rigorous specifications, giving you confidence in your experimental outcomes. We encourage you to request a quote for your specific needs and experience the benefits of sourcing directly from an experienced producer.
Key Considerations for Procurement:
- Purity: Always check the Certificate of Analysis (CoA) to verify the purity level, typically expressed as >98% or higher for research-grade materials.
- Packaging: Ensure the product is appropriately packaged to maintain its stability and prevent contamination during transit.
- Storage Conditions: Follow recommended storage guidelines, usually at room temperature or refrigerated, to preserve product integrity.
In conclusion, Boc-Orn-OH is an indispensable tool for anyone involved in peptide synthesis and related chemical research. By choosing a reputable manufacturer and supplier, you ensure the quality, consistency, and availability needed to drive your scientific endeavors forward. Contact us today to explore our offerings and secure your supply of high-quality Boc-Orn-OH.
Perspectives & Insights
Molecule Vision 7
“The 'Boc' (tert-butyloxycarbonyl) group serves as a protecting group for the alpha-amino function, a standard practice in peptide synthesis to control the reaction process.”
Alpha Origin 24
“L-ornithine itself is a non-proteinogenic amino acid, often found in urea cycle intermediates and collagen.”
Future Analyst X
“Its incorporation into peptides can impart unique structural and functional properties, making it valuable in designing peptidomimetics, therapeutic peptides, and complex biochemical tools.”