Bufogenin, identified by CAS number 465-39-4 and also known as Resibufogenin, is a complex steroidal lactone with a diverse range of physiological impacts. While its antitumor properties are well-documented, its influence on the cardiovascular and central nervous systems (CNS) presents significant avenues for research and potential therapeutic development. For scientists and procurement managers investigating treatments for cardiovascular diseases or neurological disorders, understanding the sourcing and application of Bufogenin is paramount. This article highlights the importance of Bufogenin in these research areas and guides on how to procure it effectively from reliable Bufogenin suppliers in China.

The cardiotonic effects of Bufogenin are closely linked to its mechanism of action as a specific Na+/K+-ATPase inhibitor. By modulating this critical ion pump, Bufogenin can influence cardiac muscle contractility and heart rate, making it a compound of interest for developing treatments for conditions like heart failure. Furthermore, research has indicated its potential role in managing hypertension and conditions such as preeclampsia, where dysregulation of the Na+/K+-ATPase system has been implicated. Studies have shown that Bufogenin administration can prevent the manifestations of preeclampsia in animal models, suggesting its therapeutic value.

In addition to its cardiovascular effects, Bufogenin has also been observed to impact the central nervous system. Research has explored its effects on voltage-gated sodium and potassium channels in neuronal cells, indicating a potential for modulating neuronal activity. This neuroactive profile suggests that Bufogenin could be relevant in studies related to pain management, anesthesia, and neurological disorders. For researchers in these fields, obtaining high-quality Bufogenin is essential for accurate and reproducible results.

To facilitate these critical research endeavors, sourcing Bufogenin from reputable Bufogenin manufacturers is key. We, as a dedicated chemical supplier based in China, provide high-purity Bufogenin (CAS 465-39-4) to meet the demanding requirements of pharmaceutical and scientific research. Our commitment to quality, coupled with competitive pricing, ensures that researchers can confidently buy Bufogenin for their studies. We encourage you to contact us for a quote and to learn more about how we can support your cardiovascular, neurological, and broader pharmaceutical research needs.