In the dynamic landscape of chemical manufacturing and research, access to reliable organic intermediates is paramount. 4-Bromo-1-hexylbenzene, identified by CAS number 23703-22-2, is a key chemical building block widely utilized in both industrial applications and cutting-edge research. Understanding its properties, applications, and how to procure it efficiently is crucial for scientists, formulators, and procurement professionals.

Understanding 4-Bromo-1-hexylbenzene: Properties and Reactivity

This compound, also referred to as 1-Bromo-4-hexylbenzene or 4-hexylbromobenzene, possesses the molecular formula C12H17Br and a molecular weight of 241.17 g/mol. Its molecular structure consists of a benzene ring with a bromine atom and a hexyl group positioned opposite each other (para-substitution). This structural arrangement makes it a highly versatile intermediate:

  • Reactive Bromine Site: The bromine atom is an excellent leaving group and participates readily in a variety of coupling reactions, such as Suzuki-Miyaura, Heck, and Grignard reactions. These reactions are fundamental for forming new carbon-carbon bonds and constructing complex organic molecules.
  • Influence of the Hexyl Chain: The presence of the hexyl group (a six-carbon alkyl chain) affects the compound's solubility in organic solvents and can impart specific physical properties like increased lipophilicity and influence self-assembly characteristics in synthesized materials.

Key Application Areas for 4-Bromo-1-hexylbenzene

The demand for 4-Bromo-1-hexylbenzene is driven by its critical role in several advanced fields:

  • Pharmaceutical Intermediates: It serves as a vital building block in the synthesis of active pharmaceutical ingredients (APIs). Medicinal chemists utilize its reactive bromine for constructing diverse molecular scaffolds targeting specific biological pathways.
  • Liquid Crystal Synthesis: This compound is instrumental in the creation of liquid crystalline materials used in modern display technologies. The hexyl tail helps in forming stable mesophases necessary for device performance.
  • Organic Electronics: Researchers employ 4-Bromo-1-hexylbenzene in the synthesis of organic semiconductors, charge transport materials, and polymers for applications in OLEDs, solar cells, and transistors.
  • Specialty Organic Synthesis: It is a general-purpose intermediate for creating a wide range of specialty chemicals with unique properties for various industrial uses.

Procurement Strategy: Buying from Manufacturers

For businesses needing to buy 4-Bromo-1-hexylbenzene, especially in larger quantities, engaging directly with manufacturers, particularly those in China, can be highly beneficial. Here’s what procurement professionals should consider:

Quality Assurance: Ensure the supplier offers high purity (typically 97% min) and provides a Certificate of Analysis (CoA) with each batch. Consistent quality is non-negotiable for pharmaceutical and electronic applications.

Pricing and Bulk Orders: Manufacturers often provide competitive pricing, especially for bulk purchases. Obtaining multiple quotes and negotiating terms can lead to significant cost savings.

Supplier Reliability: Look for manufacturers with a solid reputation, good communication, and reliable delivery schedules. A stable supply chain is critical for maintaining production continuity.

By understanding the importance of 4-Bromo-1-hexylbenzene (CAS: 23703-22-2) and adopting a strategic approach to sourcing from reputable manufacturers, companies can ensure they acquire the high-quality intermediates needed to drive innovation and achieve their manufacturing goals.