For professionals in the pharmaceutical and chemical research sectors, the ability to reliably source high-quality intermediates is fundamental to project success. 6-Bromo-1H-indazol-3-amine (CAS: 404827-77-6) is one such intermediate, valued for its role in synthesizing complex molecules, particularly in drug discovery. This guide provides essential insights for buyers looking to purchase this compound, emphasizing quality, purity, and effective supply chain management.

Understanding Your Needs: Specifications and Purity

Before you buy 6-Bromo-1H-indazol-3-amine, it's critical to define your specific requirements. The most crucial specification is purity, typically stated as a percentage confirmed by analytical methods like HPLC. For most advanced applications, a purity of 97% or higher is standard. Other key specifications to confirm with your supplier include:

  • Molecular Formula: C7H6BrN3
  • Molecular Weight: Approximately 212.05 g/mol
  • Appearance: Usually a white to off-white crystalline powder
  • CAS Number: 404827-77-6

A supplier’s ability to provide a detailed Certificate of Analysis (CoA) for each batch is a testament to their commitment to quality. This document should clearly outline the analytical results, confirming the purity and other critical parameters.

The Supply Chain: From Manufacturer to Your Lab

When you buy 6-Bromo-1H-indazol-3-amine, you are engaging with a supply chain that ideally starts with a primary manufacturer. Many of these manufacturers are located in regions like China, known for their extensive chemical production capabilities. A well-managed supply chain ensures:

  • Consistent Availability: Reliable suppliers maintain adequate stock or have robust production schedules to meet demand.
  • Timely Delivery: Understanding lead times, shipping options, and customs procedures is vital to avoid project delays. Working with suppliers experienced in international logistics is beneficial.
  • Cost-Effectiveness: Direct sourcing from manufacturers often yields better pricing. However, it’s important to balance cost with quality and reliability.
  • Risk Mitigation: Diversifying suppliers or having backup options can mitigate risks associated with supply chain disruptions, quality issues, or geopolitical factors.

Key Strategies for Buyers

To ensure a successful purchase of 6-Bromo-1H-indazol-3-amine:

  • Supplier Vetting: Conduct thorough research on potential suppliers. Look for established companies with good reputations, positive customer feedback, and relevant quality certifications (e.g., ISO).
  • Sample Testing: Always order samples for your own quality control testing before committing to bulk orders. This is the best way to verify that the product meets your exacting standards.
  • Clear Communication: Maintain open and clear communication with your supplier regarding specifications, order quantities, delivery schedules, and any potential issues.
  • Negotiate Terms: Don't hesitate to negotiate pricing, payment terms, and delivery conditions, especially for larger or recurring orders.
  • Understand Regulatory Requirements: Be aware of any import or usage regulations for chemical intermediates in your region.

Conclusion

Purchasing 6-Bromo-1H-indazol-3-amine requires a strategic approach that prioritizes quality, purity, and supply chain reliability. By understanding the key specifications, vetting suppliers diligently, and focusing on building strong relationships, buyers can confidently source this critical intermediate, ensuring the efficient progress of their research and development endeavors.