For procurement professionals and R&D scientists in the pharmaceutical sector, navigating the world of chemical intermediates can be complex. Ensuring the correct specifications, quality, and reliable sourcing for compounds like 2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide (CAS 15308-01-7) is crucial for successful API manufacturing. This guide aims to equip buyers with the knowledge to make informed decisions when sourcing this vital intermediate for Diclofenac synthesis.

Understanding the Intermediate:

2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide is a key building block in the synthesis pathway of Diclofenac, a prominent NSAID. Its chemical structure (C14H10Cl3NO, MW 314.59) and physical properties, typically appearing as a white or almost white crystalline powder, are well-defined. When you purchase this compound, it's essential to align these characteristics with your specific process requirements.

Key Specifications to Look For:

  • Appearance: White or almost white crystalline powder.
  • Assay: A high purity level is critical. Look for specifications indicating NLT 99.0% purity, often determined by HPLC.
  • Loss on Drying: Typically NMT 0.5%, indicating minimal moisture content.
  • Related Substances: Manufacturers should provide limits for individual and total impurities, crucial for API quality.
  • CAS Number: 15308-01-7 is the universally recognized identifier.

Why Supplier Selection Matters:

Choosing the right supplier for 2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide directly impacts your production’s success. Consider the following when evaluating potential partners:

  • Manufacturing Expertise: Does the manufacturer have a proven track record in producing pharmaceutical intermediates?
  • Quality Assurance: Do they provide comprehensive Certificates of Analysis (CoA) with each batch, detailing analytical results and methods?
  • Regulatory Compliance: Are their manufacturing processes aligned with industry best practices for pharmaceutical intermediates?
  • Supply Chain Reliability: Can they guarantee consistent availability and on-time delivery?
  • Technical Support: Is there a readily available technical team to answer queries regarding product specifications and applications?

The Advantage of Sourcing from China:

Many pharmaceutical companies look to source intermediates like CAS 15308-01-7 from experienced manufacturers in China. This is often driven by competitive price points and the vast production capacities available. However, it is crucial to partner with reputable companies that prioritize quality and transparency. By doing so, buyers can benefit from cost savings while ensuring the reliability and purity of the materials needed for Diclofenac synthesis.

Actionable Steps for Buyers:

  • Request Samples: Before committing to large orders, obtain samples for internal quality assessment.
  • Ask for CoAs: Always request a Certificate of Analysis for the specific batch you are considering.
  • Inquire about Lead Times: Understand the delivery timelines to plan your production schedule effectively.
  • Clarify Payment Terms: Discuss payment terms to ensure they align with your company's financial policies.

By following these guidelines, buyers can confidently source 2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide, ensuring the quality and efficiency of their Diclofenac API production. We are a dedicated manufacturer and supplier committed to meeting these buyer needs. Feel free to enquire for detailed product information, pricing, and availability.