For professionals engaged in chemical synthesis, particularly within the pharmaceutical and agrochemical sectors, the acquisition of reliable, high-purity intermediates is a foundational aspect of successful product development. 2-AMINO-3-NITRO-5-PICOLINE, known by its CAS number 7598-26-7, is a prominent example of such a critical building block. This article delves into the manufacturer's perspective on procuring this compound, emphasizing quality assurance, supplier selection, and market price considerations.

The Technical Profile and Industrial Importance

2-AMINO-3-NITRO-5-PICOLINE is a chemical compound with the molecular formula C6H7N3O2 and a molecular weight of 153.14. It is characterized by its appearance as a yellow to greenish-yellow crystalline powder. The strategic placement of an amino group at the 2-position, a nitro group at the 3-position, and a methyl group at the 5-position of the pyridine ring grants it significant chemical reactivity. This inherent reactivity makes it an invaluable intermediate for a multitude of organic synthesis pathways.

In the realm of pharmaceutical research and development, this compound serves as a vital precursor for the synthesis of various APIs. Its utility spans the creation of kinase inhibitors, crucial in targeted cancer therapies, and antimicrobial agents, addressing the persistent challenge of drug-resistant infections. The pyridine core is a favored scaffold in medicinal chemistry due to its ability to interact effectively with biological targets. By enabling diverse functional group modifications, 2-AMINO-3-NITRO-5-PICOLINE facilitates the design and synthesis of novel drug candidates.

Similarly, the agrochemical industry depends on this intermediate for the production of advanced crop protection agents. Its incorporation into herbicides, fungicides, and insecticides contributes to the development of formulations that offer superior efficacy, selectivity, and improved environmental profiles. As a result, it plays a role in enhancing agricultural productivity and sustainability.

Strategic Purchasing Considerations for 2-AMINO-3-NITRO-5-PICOLINE

From a manufacturer's viewpoint, sourcing 2-AMINO-3-NITRO-5-PICOLINE requires a disciplined approach to quality and supply chain management. When buyers are looking to purchase this compound, they should prioritize:

1. Purity and Quality Assurance: The critical nature of pharmaceutical and agrochemical synthesis demands intermediates of the highest purity, typically exceeding 98%, often verified by analytical techniques like HPLC or GC. Buyers should always demand comprehensive Certificates of Analysis (CoA) and understand the supplier's quality control protocols. NINGBO INNO PHARMCHEM CO.,LTD. as a manufacturer, places paramount importance on these aspects.

2. Supplier Reliability and Origin: China is a significant global manufacturing base for chemical intermediates. Identifying reputable Chinese manufacturers and suppliers is key. Factors such as production capacity, adherence to industry standards, and a history of consistent delivery are vital. Buyers often seek direct manufacturers or authorized distributors to ensure genuine product origin and dedicated support.

3. Market Pricing and Bulk Procurement: Price competitiveness is an important consideration for industrial-scale procurement. Bulk purchases generally offer more favorable pricing. Buyers should engage with suppliers like NINGBO INNO PHARMCHEM CO.,LTD. to obtain accurate quotations based on their required volumes. Understanding market dynamics and securing long-term supply agreements can also be beneficial.

In conclusion, the successful procurement of 2-AMINO-3-NITRO-5-PICOLINE hinges on a thorough understanding of its technical specifications, applications, and the global supply landscape. By partnering with experienced manufacturers and suppliers in China, such as NINGBO INNO PHARMCHEM CO.,LTD., businesses can ensure they receive high-quality intermediates essential for their innovative chemical synthesis projects.