For procurement professionals in the chemical and pharmaceutical industries, the strategic sourcing of essential intermediates like 3-Fluorobenzyl Chloride (CAS 456-42-8) is a critical function. This versatile compound serves as a cornerstone in the synthesis of numerous valuable products, making its availability and quality directly impact production cycles and final product efficacy. This guide provides insights into navigating the process of buying 3-Fluorobenzyl Chloride.

Understanding the Product: 3-Fluorobenzyl Chloride

3-Fluorobenzyl Chloride, with the CAS number 456-42-8, is an organic compound with the molecular formula C7H6ClF. It is typically supplied as a liquid. Its key chemical feature is the chloromethyl group attached to a benzene ring that also bears a fluorine atom at the meta position. This structure makes it highly reactive and useful for introducing the 3-fluorobenzyl moiety into target molecules through substitution reactions.

Industrial Applications Driving Demand

The demand for 3-Fluorobenzyl Chloride is largely driven by its utility in:

  • Pharmaceutical Synthesis: It's a common building block for synthesizing Active Pharmaceutical Ingredients (APIs), influencing drug properties like metabolic stability and receptor binding.
  • Agrochemicals: Used in the creation of pesticides, herbicides, and fungicides, contributing to enhanced crop protection solutions.
  • Research and Development: Essential for academic and industrial research labs exploring new organic reactions and creating novel chemical entities.

Key Considerations When You Buy

When making a purchase decision for 3-Fluorobenzyl Chloride, procurement professionals should focus on several key aspects:

  • Purity and Specifications: Ensure the supplier provides detailed specifications, typically a purity of 95% or higher, along with a Certificate of Analysis (COA) for each batch. This guarantees the material meets your process requirements.
  • Supplier Reliability: Look for established manufacturers and distributors with a proven track record. Companies with strong customer support and transparent business practices are preferable.
  • Price and Volume: Obtain multiple quotes for the required quantity. Bulk purchases often come with significant cost savings. Direct inquiries to manufacturers, especially those in China, can yield competitive pricing.
  • Lead Times and Logistics: Understand the supplier's lead times for delivery and their shipping capabilities, particularly for regulated chemical substances.
  • Safety Information: Always request and review the Safety Data Sheet (SDS) to understand the handling, storage, and emergency procedures associated with 3-Fluorobenzyl Chloride.

Navigating the Procurement Process

To effectively buy 3-Fluorobenzyl Chloride (CAS 456-42-8), initiating contact with potential suppliers is the first step. Clearly communicate your needs regarding quantity, purity, and any specific packaging or delivery requirements. Responsive communication and readily available documentation from the supplier are good indicators of their professionalism and reliability.

By prioritizing these factors, procurement teams can secure a consistent and high-quality supply of 3-Fluorobenzyl Chloride, ensuring the smooth operation of their research and manufacturing processes and contributing to the development of innovative chemical products.