For research and development professionals in the chemical and pharmaceutical sectors, access to reliable, high-purity intermediates is the bedrock of innovation. 5,6-Dimethoxy-1-indanone (CAS: 2107-69-9) is one such compound, valued for its application in advanced organic synthesis, particularly as a precursor for pharmaceuticals like Donepezil. This article serves as a comprehensive guide for R&D scientists and procurement managers seeking to buy this essential chemical, detailing what to look for in a supplier and the key product specifications.

What to Look for When Buying 5,6-Dimethoxy-1-indanone

When sourcing 5,6-Dimethoxy-1-indanone for your research projects, consider these critical factors:

  • Purity: The purity of chemical intermediates directly impacts the success of synthesis reactions and the quality of the final product. For 5,6-Dimethoxy-1-indanone, a purity of 98% or higher is generally recommended. Always request a Certificate of Analysis (CoA) from potential suppliers to verify this specification.
  • Physical Form: This compound typically exists as an off-white to pale yellow crystalline powder. Understanding the physical form helps in handling and storage planning.
  • CAS Number and Synonyms: Confirm that the CAS number (2107-69-9) and common synonyms (e.g., 5,6-dimethoxyindan-1-one) match your requirements. This ensures you are procuring the correct chemical entity.
  • Supplier Reputation: Partner with established chemical suppliers and manufacturers known for their quality, reliability, and customer service. Look for suppliers with a strong online presence, clear contact information, and positive industry reviews.
  • Availability and Lead Times: For R&D, having materials readily available is crucial. Inquire about stock levels and estimated delivery times from potential manufacturers. If you plan larger-scale projects, confirm their capacity to scale up production.
  • Pricing and Packaging: Obtain quotes for different quantities, as pricing can vary significantly. Ensure that the packaging is appropriate for the quantity and suitable for research laboratory use, or discuss bulk packaging options with your supplier.

The Importance of 5,6-Dimethoxy-1-indanone in Pharmaceutical R&D

5,6-Dimethoxy-1-indanone is a vital intermediate in the synthesis of Donepezil hydrochloride, a drug critical for managing symptoms associated with Alzheimer's disease. Its specific molecular structure allows for targeted chemical reactions that build the Donepezil molecule. Researchers investigating new drug candidates or optimizing existing synthetic pathways often rely on this compound. When you need to buy this intermediate, understanding its role can help you communicate your needs more effectively to suppliers and manufacturers.

Finding a Reliable Manufacturer and Supplier

When searching for a supplier of 5,6-Dimethoxy-1-indanone, consider manufacturers who offer:

  • Clear product specifications and comprehensive safety data (MSDS).
  • A robust quality management system, possibly evidenced by ISO or GMP certifications.
  • Responsive customer service and technical support.
  • Competitive pricing, especially for R&D quantities.
  • Secure and timely shipping options.

Engaging with reputable chemical suppliers, including those based in regions like China known for their chemical manufacturing expertise, can provide access to high-quality 5,6-Dimethoxy-1-indanone at competitive prices. Always perform due diligence to ensure the supplier meets your exacting standards.

Conclusion

Securing a consistent supply of high-quality 5,6-Dimethoxy-1-indanone is fundamental for successful R&D outcomes in the pharmaceutical and chemical industries. By carefully evaluating suppliers based on purity, specifications, and reliability, R&D professionals can confidently procure this essential intermediate, driving forward their critical research and development efforts.