For professionals in the pharmaceutical industry, sourcing high-quality chemical intermediates is a critical step in the drug development and manufacturing process. 3-Acetyl-2,5-dichlorothiophene (CAS: 36157-40-1) is a compound that frequently appears on procurement lists due to its significant role as a pharmaceutical intermediate. This guide aims to equip buyers with the knowledge to effectively source and purchase this vital chemical.

Understanding the Product: Key Specifications

When you intend to buy 3-Acetyl-2,5-dichlorothiophene, understanding its specifications is paramount. Typically, this compound is supplied as a white to off-white crystalline powder, with a reported melting point range of 37-40 °C. Its molecular formula is C6H4Cl2OS, and its molar mass is approximately 195.07 g/mol. The purity specification is often stated as ≥95%, although higher purities may be available from specialized suppliers. As a crucial intermediate for pharmaceutical applications, ensuring these specifications are met by the manufacturer is non-negotiable. Buyers should always request a detailed Certificate of Analysis (CoA) with their order to verify these critical parameters.

Applications Driving Demand

The demand for 3-Acetyl-2,5-dichlorothiophene is primarily driven by its utility in synthesizing Active Pharmaceutical Ingredients (APIs). Its structure allows for diverse chemical modifications, making it a flexible building block in the pharmaceutical R&D pipeline. Companies involved in drug discovery and process development often require this intermediate for synthesizing new chemical entities or optimizing existing manufacturing routes. When you plan to purchase this compound, consider the scale of your project, as this will influence the required quantity and the supplier's capacity.

Finding a Reliable Manufacturer and Supplier

Navigating the global chemical market to find a reliable source for pharmaceutical intermediates can be challenging. However, with strategic sourcing, buyers can secure high-quality products at competitive prices. Here are key considerations when looking to buy 3-Acetyl-2,5-dichlorothiophene:

  • Supplier Reputation: Look for established chemical companies with a strong reputation in the pharmaceutical intermediate sector. Reviews and testimonials from other buyers can be invaluable.
  • Manufacturing Capabilities: Verify that the manufacturer can consistently produce the required purity and quantity. Inquire about their quality control processes and any relevant certifications.
  • Pricing and Quotation: Request a detailed quote from multiple suppliers to compare pricing. However, always balance cost with quality and reliability.
  • Geographic Location: Sourcing from manufacturers in regions like China can often provide cost advantages, but it is crucial to ensure that quality standards and shipping logistics are robust.
  • Technical Support: A responsive supplier will offer technical assistance, helping you understand the product's properties and potential applications.

By focusing on these aspects, pharmaceutical companies can ensure a stable and high-quality supply of 3-Acetyl-2,5-dichlorothiophene, ultimately contributing to the successful development and production of essential medicines. For those ready to make a purchase, reaching out to known suppliers for immediate price information is the next step.