Carazolol, identified by CAS number 57775-29-8, is a chemical compound of significant interest, particularly as a pharmaceutical intermediate and research reagent. For potential buyers and researchers, understanding the synthesis pathways and crucial chemical specifications of Carazolol is paramount. This article provides an overview of these aspects, guiding informed procurement decisions.

The synthesis of Carazolol (C18H22N2O2) typically involves multi-step organic reactions. While specific proprietary methods may vary among manufacturers, a common approach often begins with a carbazole derivative and involves etherification and amination reactions to build the propanolamine side chain. The careful control of reaction conditions, including temperature, catalysts, and reaction times, is critical to achieving high yields and desired purity. Chemical suppliers, especially those in China, who specialize in fine chemicals, often have optimized synthesis routes for compounds like Carazolol.

Key chemical specifications that buyers should scrutinize when looking to buy Carazolol include its purity, typically measured by High-Performance Liquid Chromatography (HPLC). High purity, often exceeding 98% or 99%, is essential for most research applications, particularly in pharmaceutical development. Other important specifications include the melting point range, the appearance (commonly described as a yellowish solid), and the solubility in various solvents like DMF, DMSO, and ethanol. These parameters help confirm the compound's identity and suitability for specific experimental protocols.

When sourcing Carazolol, it is vital to request a Certificate of Analysis (CoA) for each batch. The CoA provides detailed information regarding the tested specifications, including purity, identification tests (e.g., NMR, Mass Spectrometry), and the levels of any identified impurities. This documentation is a cornerstone for ensuring the quality and consistency of the chemical intermediate you are purchasing.

The market offers Carazolol in various quantities, from small laboratory amounts (milligrams) to larger, bulk orders (grams or kilograms). Pricing can vary significantly based on purity, quantity, and the supplier's location and reputation. Researchers should compare quotes from multiple reputable manufacturers and suppliers to secure the best value for their investment in this critical chemical intermediate.

In conclusion, the synthesis and chemical specifications of Carazolol (CAS 57775-29-8) are critical factors for researchers and buyers. A thorough understanding of its purity, physical properties, and the documentation provided by suppliers ensures the acquisition of a high-quality chemical intermediate suitable for demanding research and development activities.