In the intricate world of pharmaceutical research and development, precise chemical building blocks are the currency of innovation. One such compound gaining attention is 8-Chloro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine, identified by its unique CAS number 140911-31-5. This molecule serves as a critical intermediate, enabling scientists to synthesize complex APIs with enhanced properties.

What is CAS 140911-31-5?

CAS 140911-31-5 refers to 8-Chloro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine. This compound features a fused ring system, the triazolopyrazine core, substituted with both a chlorine atom and a trifluoromethyl group. These functional groups are highly desirable in medicinal chemistry. The trifluoromethyl group, as previously discussed, can improve lipophilicity, metabolic stability, and binding affinity. The chlorine atom offers a reactive site for further chemical modifications, allowing for the introduction of diverse side chains essential for tailoring drug candidates.

Role as a Pharmaceutical Intermediate

As a pharmaceutical intermediate, CAS 140911-31-5 is not an API itself but rather a precursor used in the multi-step synthesis of APIs. Its specific structure makes it valuable for creating molecules with potential therapeutic applications in various disease areas. Researchers often require precise intermediates like this to build complex molecular architectures efficiently and with high purity, which is crucial for regulatory approval and therapeutic efficacy.

Sourcing and Supplier Considerations

For research institutions and pharmaceutical companies, sourcing reliable intermediates like CAS 140911-31-5 is a critical task. Identifying a reputable manufacturer and supplier from China, a major hub for fine chemical production, can provide access to high-quality materials at competitive prices. When evaluating potential suppliers, key considerations include:

  • Purity and Quality Control: Does the supplier provide detailed CoAs? Are their manufacturing processes GMP-compliant?
  • Availability and Lead Times: Can they supply the required quantities within your project timelines?
  • Technical Support: Do they have knowledgeable staff who can assist with inquiries?
  • Pricing: Is the price competitive for the quality offered? Are there discounts for bulk purchases?

For those looking to buy 8-Chloro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine, partnering with experienced chemical suppliers ensures that your R&D efforts are supported by reliable, high-quality materials. These intermediates are vital tools in the ongoing quest for new and improved medicines.