The relentless pursuit of effective antiviral therapies relies on a sophisticated understanding of chemical synthesis and the availability of crucial building blocks. Among these, CAS 142217-80-9 stands out as a significant pharmaceutical intermediate, playing a pivotal role in the manufacturing of modern antiviral drugs. This article explores the chemical importance of this compound and its applications within the pharmaceutical industry.

Chemically identified as 6-(Benzyloxy)-9-((1S,3R,3S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl)-N-((4-methoxyphenyl)diphenylmethyl)-9H-purin-2-amine, CAS 142217-80-9 is a complex organic molecule. Its structure, featuring a purine core with extensive benzyl ether protection and a unique cyclopentyl substituent, makes it an ideal precursor for specific antiviral agents. With a molecular formula of C53H49N5O4 and a molecular weight of 819.99, this compound's precise architecture is key to its functionality.

The primary application of this intermediate lies in the synthesis of entecavir, a potent antiviral medication primarily used in the treatment of chronic Hepatitis B virus (HBV) infection. Entecavir functions by inhibiting viral DNA polymerase, thereby reducing the viral load in the body and mitigating liver damage. The synthesis of such complex drugs requires high-purity intermediates like CAS 142217-80-9 to ensure the final API is both effective and safe. Sourcing this compound from a reliable pharmaceutical intermediate manufacturer is paramount for pharmaceutical companies engaged in entecavir production.

The synthesis of CAS 142217-80-9 itself involves multi-step organic reactions, often requiring specialized reagents and controlled conditions. Manufacturers like those found in China are adept at performing these complex syntheses at scale. For procurement managers, understanding the specifications and purity levels offered by a supplier for antiviral drug synthesis is critical. A high-purity intermediate reduces the burden of downstream purification and ensures consistent drug product quality.

When considering the CAS 142217-80-9 price quote, it's important to recognize that the complexity of its synthesis contributes to its value. However, strategic sourcing from experienced manufacturers can lead to competitive pricing, especially for bulk orders. Companies may also explore custom synthesis pharmaceutical intermediate options if specific modifications or higher purity levels are required for their R&D projects.

In conclusion, CAS 142217-80-9 represents more than just a chemical compound; it is a vital link in the chain of producing life-saving antiviral medications. Its precise chemical structure and high purity, ensured by diligent manufacturing and sourcing practices, are fundamental to the efficacy and safety of the final pharmaceutical products.