Decoding CAS 24016-03-3: Properties and Applications of 2-Amino-3-benzyloxypyridine
In the realm of organic chemistry and pharmaceutical manufacturing, precise understanding of chemical compounds is vital for successful synthesis and development. 2-Amino-3-benzyloxypyridine, identified by its CAS number 24016-03-3, is a compound that plays a significant role as an intermediate in the creation of advanced therapeutic agents.
Chemically, 2-Amino-3-benzyloxypyridine is a derivative of pyridine. It typically presents as white to slightly yellow crystals, a characteristic that aids in initial visual quality assessment. Its molecular formula is C12H12N2O, with a molecular weight of 200.24. The compound exhibits a melting point in the range of 92-94 °C, indicating its solid state at room temperature. While slightly soluble in chloroform and methanol, its primary utility lies in its chemical reactivity for further synthesis rather than its solvent properties.
The applications of 2-Amino-3-benzyloxypyridine are primarily centered around its use as a pharmaceutical intermediate. It is a key building block in the synthesis of molecules that target specific biological processes. Notably, it is employed in the preparation of pyridinyl/pyridazinyloxymethyl substituted Raf kinase inhibitors. These inhibitors are crucial for developing targeted cancer therapies, as Raf kinases are integral to cell signaling pathways often implicated in uncontrolled cell growth.
Beyond oncology, research indicates its use in synthesizing compounds that exhibit inhibitory activity against mitogen-activated protein kinase p38α. This highlights its potential in various therapeutic areas where modulating inflammatory or cellular stress responses is beneficial. For researchers and manufacturers, sourcing this intermediate with high purity (≥99.0%) is essential for achieving reliable and reproducible synthesis results. If you are looking to buy this compound for your R&D projects or commercial needs, seeking out trusted suppliers in China ensures both quality and competitive pricing.
Understanding the detailed properties and applications of intermediates like 2-Amino-3-benzyloxypyridine empowers chemists and procurement specialists to make informed decisions. Whether you are developing novel pharmaceuticals or optimizing existing synthesis routes, this compound offers significant versatility as a foundational chemical component. For more information on procurement and availability, contacting experienced suppliers is the recommended step.
Perspectives & Insights
Molecule Vision 7
“Notably, it is employed in the preparation of pyridinyl/pyridazinyloxymethyl substituted Raf kinase inhibitors.”
Alpha Origin 24
“These inhibitors are crucial for developing targeted cancer therapies, as Raf kinases are integral to cell signaling pathways often implicated in uncontrolled cell growth.”
Future Analyst X
“Beyond oncology, research indicates its use in synthesizing compounds that exhibit inhibitory activity against mitogen-activated protein kinase p38α.”