In the intricate landscape of chemical synthesis, specific CAS numbers serve as unique identifiers for chemical compounds, facilitating precise communication and procurement. CAS 4318-56-3, known scientifically as 6-Chloro-3-methyluracil, is a compound of significant interest, particularly within the pharmaceutical industry. This article aims to provide a clear overview of this chemical, its key properties, prevalent applications, and guidance for sourcing it from reliable manufacturers and suppliers.

Decoding CAS 4318-56-3: 6-Chloro-3-methyluracil

6-Chloro-3-methyluracil is a substituted pyrimidine derivative with the molecular formula C5H5ClN2O2 and a molecular weight of approximately 160.56 g/mol. Its common synonyms include 3-methyl-6-chlorouracil and 6-chloro-3-methyl-1H-pyrimidine-2,4-dione. Typically appearing as a white powder, it is characterized by a melting point of around 278-280°C (with decomposition).

Key Properties and Handling

From a safety perspective, 6-Chloro-3-methyluracil is generally categorized with hazard statements like H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Standard precautionary statements such as P261 (Avoid breathing dust/fume/gas/mist/vapors/spray) and P280 (Wear protective gloves/protective clothing/eye protection/face protection) are recommended. Proper handling in a well-ventilated area and use of appropriate personal protective equipment (PPE) are crucial when working with this compound.

Primary Applications in Pharmaceutical Synthesis

The primary value of 6-Chloro-3-methyluracil lies in its role as a crucial intermediate in the synthesis of important pharmaceuticals. It is widely recognized as a key building block for:

  • Alogliptin: An oral antidiabetic drug used to treat Type 2 diabetes.
  • Trelagliptin: Another DPP-4 inhibitor for managing Type 2 diabetes.
  • Antibacterial Agents: Research has explored its potential in developing novel antibiotics.

These applications underscore the demand for high-purity 6-Chloro-3-methyluracil in the pharmaceutical sector.

Sourcing Considerations: Finding a Reliable Supplier

When you need to buy CAS 4318-56-3, partnering with a reputable manufacturer and supplier is paramount. Look for suppliers who:

  • Offer high purity (e.g., ≥99% by HPLC).
  • Provide comprehensive product specifications and safety data sheets (SDS).
  • Have robust quality control processes.
  • Can guarantee consistent supply and competitive pricing.
  • Offer efficient global logistics for timely delivery.

As a leading supplier in China, we are dedicated to meeting these requirements. We invite you to contact us for your inquiries and to purchase 6-Chloro-3-methyluracil, ensuring a high-quality and reliable supply for your pharmaceutical projects.