The global pharmaceutical industry relies heavily on a consistent supply of high-quality chemical intermediates for the synthesis of Active Pharmaceutical Ingredients (APIs). Among these essential compounds is (S)-4-(1-Boc-amino-ethyl)-benzoic acid methyl ester, identified by its CAS number 847728-90-9. This chiral intermediate is gaining recognition for its versatility and critical role in developing advanced therapeutic agents. For procurement specialists and R&D scientists, understanding its specifications and sourcing from reliable suppliers is key to successful API production.

CAS 847728-90-9, also known as (S)-methyl 4-(1-((tert-butoxycarbonyl)amino)ethyl)benzoate, is characterized by its specific stereochemistry and functional groups, making it a valuable building block in organic synthesis. Its purity, typically exceeding 98% by HPLC, is paramount for ensuring the quality and efficacy of the resulting APIs. The compound presents as a white or off-white crystalline powder, a common and manageable physical form for laboratory and industrial handling. When you aim to buy this intermediate, prioritizing these specifications is essential.

The utility of CAS 847728-90-9 is amplified by its structural features. The tert-butoxycarbonyl (Boc) group provides a robust yet easily removable protecting group for the amine functionality, crucial for controlling reactivity during complex syntheses. The presence of the bromophenyl ring allows for further chemical modifications through various cross-coupling reactions, such as Suzuki-Miyaura or Buchwald-Hartwig couplings. These reactions are fundamental in constructing elaborate molecular architectures required for modern drug candidates, including those targeting the central nervous system or acting as enzyme inhibitors. Seeking out a reputable manufacturer in China can ensure access to these sophisticated intermediates.

For professionals in API manufacturing, identifying a dependable supplier for CAS 847728-90-9 is critical for maintaining production schedules and ensuring product quality. NINGBO INNO PHARMCHEM CO.,LTD. is a prominent manufacturer and supplier that provides this intermediate, understanding the strict requirements of the pharmaceutical sector. By partnering with such a supplier, companies can secure a consistent and competitive price for this vital component, supporting their ongoing production needs.

The application of CAS 847728-90-9 extends across various phases of drug development, from early-stage research synthesis to process development for commercial API manufacturing. Its chiral nature makes it particularly important for creating enantiomerically pure drugs, a growing trend in pharmaceutical development to minimize side effects and maximize therapeutic benefit. Therefore, understanding the chemical attributes and sourcing strategies for this key intermediate is a strategic imperative for any pharmaceutical company aiming for efficiency and innovation in API synthesis.