The pharmaceutical industry's constant pursuit of effective treatments for challenging infections drives the demand for specialized chemical intermediates. (Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-ethoxyiminoacetic acid, identified by CAS number 75028-24-9, plays a pivotal role in this arena as a key precursor for the antibiotic Ceftaroline. For procurement managers and R&D scientists, understanding the market dynamics and sourcing options for this compound is crucial.

The Chemical Profile of CAS 75028-24-9

Chemically, (Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-ethoxyiminoacetic acid has the molecular formula C6H8N4O3S and a molecular weight of 216.22. It typically presents as a pale beige solid with a melting point around 190-193°C (with decomposition). Its utility as a pharmaceutical intermediate, particularly for Ceftaroline, underscores the need for high purity and consistent batch-to-batch quality. When a manufacturer specifies a purity of 98% (HPLC), it indicates a reliable product suitable for complex organic synthesis.

Finding a Reliable Manufacturer for Bulk Orders

For companies requiring substantial quantities of CAS 75028-24-9, identifying a dependable manufacturer is a strategic imperative. Many global pharmaceutical producers turn to China for cost-effective sourcing of such intermediates. When evaluating a supplier, key due diligence steps include:

  • Manufacturing Capabilities: Assess the supplier's production capacity, quality control systems (e.g., ISO certifications), and track record in producing pharmaceutical intermediates.
  • Technical Support: A good supplier will offer comprehensive technical data, including Certificates of Analysis (CoA) and Safety Data Sheets (SDS), and be responsive to inquiries.
  • Logistics and Export Experience: Ensure the supplier has experience in international shipping and can handle the complexities of global export regulations.
  • Pricing and Contract Terms: Negotiating favourable pricing for bulk purchases is essential for managing project budgets. Clear contract terms regarding quality, delivery, and payment are also vital.

By diligently evaluating potential partners, businesses can secure a stable and cost-efficient supply of this critical Ceftaroline precursor. The ability to buy this intermediate from a reputable manufacturer in China can provide a significant competitive advantage.

In summary, for those in the pharmaceutical sector seeking to buy (Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-ethoxyiminoacetic acid, understanding its role and carefully selecting a supplier are the cornerstones of successful procurement. Leveraging the manufacturing strengths of China offers a pathway to acquire this vital compound efficiently.