In the realm of chemical synthesis, having access to reliable and high-quality building blocks is fundamental for researchers and manufacturers. Boc-R-3-Amino-3-(2-hydroxyphenyl)propionic Acid, identified by its CAS number 500788-88-5, is one such critical intermediate. This compound is a specialized amino acid derivative that finds extensive use in peptide synthesis and as a precursor in the development of various fine chemicals and pharmaceutical agents. Understanding its chemical structure, properties, and how to effectively source it is vital for efficient synthesis planning.

The molecular structure of Boc-R-3-Amino-3-(2-hydroxyphenyl)propionic Acid features a Boc-protected amine group, a carboxylic acid functionality, and a chiral center at the beta-carbon. The presence of the 2-hydroxyphenyl group adds a distinct aromatic feature with a hydroxyl substituent, influencing its reactivity and potential interactions. The Boc group is a common protecting group in organic synthesis, particularly in peptide chemistry, due to its stability under various reaction conditions and its facile removal under acidic treatment. This makes the compound amenable to straightforward incorporation into larger molecular frameworks.

For scientists and procurement specialists, the decision to buy this compound often hinges on purity and availability from a trusted manufacturer. With a typical purity specification of 97% or higher (often verified by HPLC), this intermediate ensures that synthetic pathways are clean and efficient. When looking to purchase, it is advisable to compare offerings from various suppliers, particularly those that specialize in amino acids and their derivatives. Companies seeking bulk quantities may find advantageous pricing from established manufacturers in regions like China, known for their robust chemical manufacturing capabilities.

The synthesis applications are diverse. In peptide synthesis, it acts as a non-natural amino acid that can introduce conformational constraints or specific functional interactions into peptide sequences, thereby modulating biological activity. Beyond peptides, it serves as a chiral building block for creating complex organic molecules, including potential drug candidates for pharmaceutical applications. The 2-hydroxyphenyl group can be further functionalized, or its presence can influence the electronic properties of the final molecule. Reliable suppliers will provide comprehensive product specifications and support, including safety data sheets (SDS) and certificates of analysis (CoA), to ensure researchers can confidently use the material.

In conclusion, Boc-R-3-Amino-3-(2-hydroxyphenyl)propionic Acid is a valuable chemical building block for advanced synthesis. Its utility in peptide chemistry and pharmaceutical development underscores the importance of securing a high-quality supply. By partnering with a reputable manufacturer and supplier, researchers and chemical engineers can ensure they have access to this critical intermediate, enabling them to drive innovation and achieve their synthesis objectives efficiently and effectively. When you need to buy, always prioritize quality and supplier reliability.