Understanding the fundamental chemical properties and synthetic utility of key intermediates is crucial for scientific progress. Fmoc-Sta-OH, identified by its CAS number 158257-40-0, is one such compound that plays a significant role in modern chemical synthesis, particularly in the realm of peptide chemistry. NINGBO INNO PHARMCHEM CO.,LTD. is a leading provider of this essential building block, offering high-quality material to researchers worldwide.

Chemically, Fmoc-Sta-OH is a derivative of statine, a non-proteinogenic amino acid characterized by a unique hydroxyl group adjacent to a carboxyl group. The presence of the Fmoc protecting group on the amino terminus makes it ideally suited for Fmoc solid-phase peptide synthesis (SPPS). This protective group is easily removed under mild basic conditions, allowing for sequential coupling reactions without damaging the peptide chain. The molecular formula of Fmoc-Sta-OH is C23H27NO5, with a molecular weight of 397.46 g/mol. Its melting point typically ranges between 92-94°C, indicating its solid state at room temperature. These precise chemical specifications, provided by manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., are vital for experimental planning and execution.

The primary application of Fmoc-Sta-OH lies in the synthesis of peptides that require enhanced stability against enzymatic degradation. By incorporating the statine residue, researchers can create peptides that are more resistant to proteases, thereby increasing their in vivo half-life and therapeutic potential. This makes Fmoc-Sta-OH a valuable tool for drug discovery and development, especially in creating potent enzyme inhibitors or modified peptide drugs. The ability to purchase Fmoc-Sta-OH from NINGBO INNO PHARMCHEM CO.,LTD. ensures access to a reliable source of this key intermediate.

Moreover, the versatility of Fmoc-Sta-OH extends to its utility in creating novel chemical entities and in bioconjugation processes. Its functional groups can be leveraged for various coupling reactions, enabling the attachment of peptides to carriers, probes, or solid supports. This broad applicability underscores its importance in diverse chemical synthesis endeavors. NINGBO INNO PHARMCHEM CO.,LTD., as a prominent chemical supplier, plays a crucial role in making this versatile compound accessible, thereby supporting innovation across multiple scientific disciplines.

In conclusion, Fmoc-Sta-OH is a cornerstone compound in modern chemical synthesis, particularly for those working with peptide chemistry and pharmaceutical development. Its well-defined chemical properties and significant synthetic advantages make it an indispensable reagent. NINGBO INNO PHARMCHEM CO.,LTD. is a trusted partner for researchers seeking this vital compound, contributing to the advancement of chemical science and its applications.