N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methacrylamide (CAS 90357-53-2) is a specialized organic chemical intermediate that plays a crucial role in various sophisticated synthesis processes, particularly within the pharmaceutical industry. Its unique chemical structure makes it a valuable building block, and understanding its properties and supply chain is vital for R&D scientists and procurement specialists. As a prominent manufacturer and supplier, we offer insights into this important compound.

The compound's chemical identity is further clarified by its synonyms, such as N-Methacryloyl-4-cyano-3-trifluoromethylaniline. Its molecular formula is C12H9F3N2O, with a molecular weight of approximately 254.21 g/mol. Physically, it typically presents as a white to off-white crystalline powder, which is advantageous for handling and integration into synthesis workflows. Critical to its application is its purity, with most commercial sources offering levels of 98.0% or higher, as verified by Gas Chromatography (GC).

The chemical properties of N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methacrylamide are defined by its functional groups. The methacrylamide portion contains a reactive double bond, making it a monomer that can undergo polymerization. This characteristic requires careful storage and handling to prevent unwanted reactions. The presence of the trifluoromethyl and cyano groups on the phenyl ring influences its electronic properties and reactivity, making it a versatile intermediate for regioselective synthesis. Its melting point, generally in the range of 137-143°C, is another key parameter indicating its solid-state stability.

Safety information is also a significant consideration. The compound is classified as hazardous and requires appropriate safety precautions during handling and storage. Recommended storage conditions often involve refrigeration (2-8°C) to maintain its integrity and prevent degradation or polymerization. Its classification as UN3077, Hazard Class 9, underscores the need for responsible management and disposal.

For organizations looking to buy N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methacrylamide, securing a reliable supply is essential for project continuity. We, as a dedicated manufacturer and supplier, provide this intermediate with a focus on high purity, consistent quality, and dependable delivery. Our commitment to excellence ensures that researchers and manufacturers can confidently procure this critical chemical for their advanced synthesis needs. Contact us to learn more about our product offerings and to request a quote for your supply requirements.