Chemical Intermediate Spotlight: Sodium 2-Hydroxybutyrate for Pharma Synthesis
In the complex world of pharmaceutical synthesis, the role of chemical intermediates cannot be overstated. They are the foundational building blocks upon which APIs are constructed, and their quality directly influences the success of drug development. Sodium 2-Hydroxybutyrate, known by its CAS number 5094-24-6, is one such indispensable intermediate, vital for the production of critical pharmaceuticals like Idelalisib.
This compound, typically presented as a white to off-white crystalline powder, possesses a molecular formula of C4H7NaO3 and a molecular weight of 126.09 g/mol. Its chemical structure and physical properties, including a melting point of 133-135°C, make it amenable to various synthetic processes. However, the most crucial characteristic for its application in pharmaceutical manufacturing is its purity. A high assay, generally ≥98.0%, is essential to ensure the integrity and efficacy of the final drug product. Researchers and procurement specialists must prioritize sourcing from manufacturers who guarantee this level of purity.
The primary application for Sodium 2-Hydroxybutyrate that drives its market demand is its use as a key intermediate in the synthesis of Idelalisib, a targeted therapy used in treating specific forms of leukemia. The complexity of such syntheses means that consistent quality and reliable supply of intermediates are paramount. For companies looking to purchase Sodium 2-Hydroxybutyrate, identifying a dependable supplier who can provide consistent quality and potentially offer bulk pricing is a strategic advantage. Suppliers based in China are often a strong option due to their manufacturing scale and competitive pricing.
When evaluating potential suppliers, buyers should always request comprehensive documentation, such as Certificates of Analysis (CoA) and Safety Data Sheets (SDS). These documents provide essential information about the product's purity, physical properties, and handling instructions. Establishing a relationship with a trusted Sodium 2-Hydroxybutyrate manufacturer that can meet rigorous quality standards and production volumes is key to ensuring uninterrupted research and development or commercial production.
In conclusion, Sodium 2-Hydroxybutyrate is a chemical intermediate of significant importance in the pharmaceutical industry. Its quality and availability are directly tied to the success of complex drug syntheses. By focusing on high purity and partnering with reputable manufacturers and suppliers, companies can secure the essential building blocks needed for developing advanced therapeutics. We are a leading provider of this critical intermediate, committed to quality and customer satisfaction.
Perspectives & Insights
Core Pioneer 24
“Suppliers based in China are often a strong option due to their manufacturing scale and competitive pricing.”
Silicon Explorer X
“When evaluating potential suppliers, buyers should always request comprehensive documentation, such as Certificates of Analysis (CoA) and Safety Data Sheets (SDS).”
Quantum Catalyst AI
“These documents provide essential information about the product's purity, physical properties, and handling instructions.”