In the vast landscape of chemical manufacturing and research, understanding the utility and sourcing of key intermediates is fundamental for success. 2-Bromophenylboronic Acid (CAS 244205-40-1) is one such compound that offers significant value across multiple industries, from advanced electronics to pharmaceuticals. For procurement managers and R&D scientists, a clear understanding of this chemical intermediate can unlock new possibilities in product development and synthesis.

What is 2-Bromophenylboronic Acid?

2-Bromophenylboronic Acid is an organoboron compound characterized by a phenyl ring substituted with both a bromine atom and a boronic acid group (-B(OH)2) at adjacent positions. Its chemical formula is C6H6BBrO2, and it typically presents as a white to off-white powder. With a molecular weight of approximately 200.83 g/mol and a purity often exceeding 99%, it is a highly functionalized building block. The presence of both a halogen (bromine) and a boronic acid group makes it exceptionally versatile in organic synthesis.

Key Applications and Reactions

The primary utility of 2-Bromophenylboronic Acid stems from its role in palladium-catalyzed cross-coupling reactions. Chief among these is the Suzuki coupling, where it readily reacts with aryl or vinyl halides/triflates to form new carbon-carbon bonds. This capability is critical for:

  • OLED Material Synthesis: It's a key component in creating complex organic molecules for OLED displays, contributing to their luminescence and charge transport properties.
  • Pharmaceutical Synthesis: As a pharmaceutical intermediate, it aids in constructing the complex molecular frameworks of potential drug candidates.
  • Fine Chemical Production: It serves as a versatile building block for various fine chemicals used in diverse industrial applications.
  • Catalysis: Its boronic acid functionality allows it to be used in catalytic processes, including greener amidations.

Procurement and Supplier Selection in China

For businesses looking to buy 2-Bromophenylboronic Acid, China offers a robust market with numerous manufacturers and suppliers. When selecting a supplier, it is crucial to evaluate factors such as product purity, consistency, lead times, and customer support. Companies that prioritize sourcing from established China-based chemical manufacturers often benefit from competitive pricing and the ability to acquire materials in varying quantities, from laboratory-scale grams to industrial-scale tons. Always request a Certificate of Analysis (CoA) to confirm product specifications and ensure suitability for your intended application.

Conclusion

2-Bromophenylboronic Acid is more than just a chemical; it's an enabler of innovation. Whether you are developing next-generation displays or synthesizing life-saving medications, this intermediate provides the chemical reactivity and structural features needed for success. By understanding its properties and leveraging the sourcing advantages offered by China's chemical industry, R&D scientists and procurement managers can effectively integrate this compound into their critical projects.