The Chemical Journey: Synthesis and Application of 2-(3-Benzoylphenyl)propionitrile
The world of fine chemicals is driven by synthesis – the intricate process of creating molecules that form the backbone of countless industries. For those in pharmaceutical manufacturing and R&D, understanding the journey of key intermediates like 2-(3-Benzoylphenyl)propionitrile (CAS 42872-30-0) is essential. This compound, characterized by its chemical formula C16H13NO and a molecular weight of 235.28, is renowned for its pivotal role in the production of Ketoprofen.
The synthesis of 2-(3-Benzoylphenyl)propionitrile typically involves several steps in organic chemistry, often starting from readily available benzophenone derivatives. While specific proprietary synthesis routes vary among manufacturers, the goal is always to achieve high purity, typically exceeding 98.0% as confirmed by GC analysis. The resulting white to almost white crystalline powder is then ready for its primary application.
The most significant application of 2-(3-Benzoylphenyl)propionitrile is its use as a precursor in the synthesis of Ketoprofen. Ketoprofen is a widely prescribed nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, inflammation, and stiffness associated with various conditions like arthritis. The conversion of 2-(3-Benzoylphenyl)propionitrile to Ketoprofen involves specific chemical reactions that transform the nitrile group and other functionalities into the final drug molecule. Ensuring a stable and quality supply of this intermediate is thus directly linked to the consistent production of this important medication.
For businesses that need to buy this compound, partnering with reliable suppliers and manufacturers is key. Companies looking for a stable supply of this CAS number can find reputable sources, particularly among manufacturers in China, who offer competitive pricing and consistent quality. When sourcing, it's important to consider not just the price but also the supplier's ability to provide thorough documentation and maintain supply chain integrity.
In essence, 2-(3-Benzoylphenyl)propionitrile represents a critical link in the pharmaceutical value chain. Its efficient synthesis and reliable availability from trusted suppliers enable the consistent manufacturing of essential drugs. For R&D scientists and procurement managers, understanding its chemical journey and application is fundamental to successful operations.
Perspectives & Insights
Nano Explorer 01
“This compound, characterized by its chemical formula C16H13NO and a molecular weight of 235.”
Data Catalyst One
“The synthesis of 2-(3-Benzoylphenyl)propionitrile typically involves several steps in organic chemistry, often starting from readily available benzophenone derivatives.”
Chem Thinker Labs
“While specific proprietary synthesis routes vary among manufacturers, the goal is always to achieve high purity, typically exceeding 98.”