For chemists and procurement specialists in the pharmaceutical and fine chemical sectors, understanding the detailed chemical profile of key intermediates is fundamental. 1-(2-Iodoethyl)-4-octylbenzene (CAS 162358-07-8) is a compound of significant interest, primarily recognized for its indispensable role in the synthesis of Fingolimod. This article aims to provide a comprehensive overview of its chemical properties, applications, and guide potential buyers on how to effectively source this vital compound, whether for laboratory research or industrial-scale manufacturing. If you are looking to buy 1-(2-iodoethyl)-4-octylbenzene, knowing its characteristics is your first step.

Chemical Identity and Physical Characteristics

1-(2-Iodoethyl)-4-octylbenzene, also known as 4-octylphenethyl iodide or simply as 1-(2-iodoethyl)-4-octylbenzene, has the chemical formula C16H25I and a molecular weight of approximately 344.274 g/mol. Its physical appearance is typically described as a liquid, ranging from colourless to yellow or brown, depending on purity and storage conditions. The compound's density is around 1.3 g/cm³, and it has a relatively high boiling point, approximately 367.9 °C at 760 mmHg, indicating low volatility at standard temperatures.

Role in Pharmaceutical Synthesis: The Fingolimod Connection

The primary importance of 1-(2-Iodoethyl)-4-octylbenzene lies in its function as a key intermediate in the synthesis of Fingolimod. Fingolimod is a crucial pharmaceutical agent, and the efficient production of this API relies heavily on the availability and quality of its precursors. Manufacturers producing this intermediate are expected to adhere to stringent quality control measures, ensuring an assay of ≥98.0% to meet the demands of pharmaceutical synthesis. For those involved in research, sourcing 4-octylphenethyl iodide for R&D allows for exploration of its reactivity and potential in various synthetic pathways.

Sourcing Strategies: Finding a Reliable Manufacturer and Supplier

When seeking to procure 1-(2-Iodoethyl)-4-octylbenzene, it is vital to partner with reputable manufacturers and suppliers. Companies based in China are prominent in the global supply of such intermediates, often offering competitive pricing for CAS 162358-07-8. Key considerations when selecting a supplier include their adherence to quality standards, the provision of comprehensive Certificates of Analysis (CoAs), and their ability to ensure consistent supply. Understanding the Fingolimod intermediate price trends can also inform procurement decisions, but it should be balanced with the supplier's overall reliability and quality assurance practices.

Technical Specifications and Handling

Beyond its primary application, its chemical structure suggests versatility in organic synthesis. The iodoethyl group is a good leaving group, facilitating nucleophilic substitution reactions, while the octylbenzene moiety provides lipophilicity. For optimal stability, the compound should be stored in a cool, ventilated place, protected from light and moisture. Researchers and production managers should always consult the Material Safety Data Sheet (MSDS) provided by the supplier for detailed handling and safety information.

In summary, 1-(2-Iodoethyl)-4-octylbenzene is a chemically significant intermediate with critical applications in pharmaceutical manufacturing. By understanding its properties and engaging with trusted suppliers, businesses can ensure they acquire this compound reliably and efficiently, supporting both research endeavors and large-scale production needs.