For professionals in the chemical and allied industries, a thorough understanding of key intermediates is crucial for successful research, development, and manufacturing. 2,5-Difluorobenzaldehyde (CAS 2646-90-4) is one such compound that merits close examination due to its versatile applications. This article provides a detailed overview of its chemical profile, including its properties, CAS number, and primary uses, aiming to inform procurement managers, research scientists, and formulation chemists.

Chemical Identity and Properties

2,5-Difluorobenzaldehyde, also known by synonyms such as 2,5-difluorobenzaldehyde, has the molecular formula C7H4F2O. Its CAS Registry Number is 2646-90-4. Physically, it is described as a light yellow clear liquid. Key properties include a density of 1.308 g/mL at 25 °C, a boiling point of 67-69 °C at 17 mm Hg, and a flash point of 138 °F, indicating it is a combustible liquid requiring careful handling. Its refractive index is noted as n20/D 1.498, and it possesses a vapor pressure of 1.16 mmHg, suggesting moderate volatility.

Purity Standards and Analysis

For industrial applications, the purity of 2,5-Difluorobenzaldehyde is a critical parameter. Standard analysis typically requires a purity of ≥98.0%, with actual test results often exceeding this benchmark, such as 98.7% purity. This high degree of purity is essential for its role as an intermediate, ensuring predictable reactivity and minimizing the formation of unwanted byproducts in downstream synthesis processes. Sourcing from a reliable 2,5-Difluorobenzaldehyde manufacturer ensures these quality standards are met.

Key Applications: A Multifaceted Intermediate

The utility of 2,5-Difluorobenzaldehyde spans several vital sectors:

  • Pharmaceuticals: It serves as a crucial intermediate in the synthesis of various APIs. The fluorinated structure can enhance drug efficacy, stability, and bioavailability.
  • Pesticides: In the agrochemical industry, it is used to create more effective and persistent pest control agents, contributing to improved crop yields.
  • Liquid Crystal Materials: Its properties make it valuable in the production of liquid crystals, which are essential components for modern electronic displays in devices like smartphones and televisions.

Sourcing and Supplier Information

When seeking to buy 2,5-Difluorobenzaldehyde, it is advisable to connect with established chemical suppliers and manufacturers. Companies specializing in fine chemical intermediates, particularly those with a strong presence in China, are key resources. Requesting a quote for 2,5-Difluorobenzaldehyde will allow you to compare pricing and quality specifications from various providers. Understanding lead times and minimum order quantities is also important for effective procurement planning.

Conclusion: A Cornerstone for Chemical Innovation

2,5-Difluorobenzaldehyde is a testament to the enabling power of specialty chemical intermediates. Its well-defined properties and diverse applications make it indispensable for innovation across the pharmaceutical, agricultural, and electronics industries. By ensuring high purity and reliable sourcing, professionals can fully leverage the potential of this critical compound.