For professionals engaged in pharmaceutical synthesis and advanced chemical research, a deep understanding of the chemical properties of key intermediates is fundamental. 2-(Aminomethyl)-5-methylpyrazine, identified by CAS number 132664-85-8, is one such compound. This pyrazine derivative, also known as 5-Methyl-2-pyrazinemethanamine, possesses a unique molecular structure that makes it highly valuable in the creation of complex organic molecules, particularly within the pharmaceutical industry.

The chemical profile of 2-(Aminomethyl)-5-methylpyrazine includes several key physical and chemical characteristics that are important for its application and handling. Typically supplied with a purity of 97% or higher (often verified by Gas Chromatography), this compound exhibits a characteristic appearance ranging from colorless to yellow or green, often in a liquid form. Important physical properties include a density of approximately 1.09 and a refractive index in the range of 1.5380-1.5430. Its boiling point is documented around 216.2 ± 35.0 °C (predicted), indicating its stability under certain thermal conditions. Storage recommendations often include refrigeration to maintain its integrity and shelf-life.

In terms of its chemical reactivity, the presence of the primary amine group (-NH2) on the methyl side chain attached to the pyrazine ring is a key functional feature. This amine group readily participates in various reactions, such as acylation, alkylation, and condensation, making it an excellent nucleophile and a versatile building block for synthesizing more complex structures. The pyrazine ring itself contributes to the overall electronic and steric properties of the molecule, influencing its behavior in further chemical transformations.

Researchers and procurement specialists should always refer to the manufacturer's detailed specifications and safety data sheets for the most accurate and up-to-date information. Understanding these properties allows for better process design, safe handling, and effective application of 2-(Aminomethyl)-5-methylpyrazine in R&D projects and commercial manufacturing. For those looking to purchase this intermediate, focusing on suppliers who provide comprehensive technical data alongside their products ensures a reliable foundation for your synthesis needs.