Understanding the detailed chemical profile of specialized intermediates is fundamental for chemists aiming to utilize them effectively in synthesis and research. 2-Bromo-5-(4-methylphenyl)sulfonylpyrrolo[2,3-b]pyrazine, identified by CAS number 1201186-54-0, is a prime example of such a compound, offering a unique combination of structural features that make it valuable in various chemical applications, particularly within the pharmaceutical sector. As a leading chemical manufacturer and supplier, we are committed to providing comprehensive information about our products.

The molecular formula for this compound is C13H10BrN3O2S, with a molecular weight of approximately 352.206 g/mol. Its structure is characterized by a fused bicyclic system, the pyrrolo[2,3-b]pyrazine core, which is a nitrogen-rich heterocycle. This core structure is inherently interesting due to its presence in numerous biologically active molecules and its potential for diverse functionalization. Attached to this core, at the C2 position, is a bromine atom, a highly versatile functional group in organic synthesis. Bromine serves as an excellent leaving group in nucleophilic substitution reactions and is particularly adept at participating in metal-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Heck, and Sonogashira couplings. These reactions are indispensable for forming carbon-carbon bonds and building complex molecular frameworks.

Further enhancing its synthetic utility is the 4-methylphenylsulfonyl (tosyl) group attached to the nitrogen atom at the N5 position of the pyrrolo[2,3-b]pyrazine system. The sulfonyl group is electron-withdrawing, which can influence the reactivity of the heterocyclic core. The tosyl group itself can sometimes act as a directing group or a protecting group that can be removed under specific conditions. This combination of a reactive halide and a modifiable sulfonyl moiety makes 2-Bromo-5-(4-methylphenyl)sulfonylpyrrolo[2,3-b]pyrazine a potent building block for medicinal chemists and synthetic organic chemists alike.

When sourcing such complex intermediates, it is crucial to buy from reliable manufacturers who can guarantee the stated chemical properties and provide them in the required purity. We, as a Chinese chemical supplier, ensure that our products meet high standards. Whether you are conducting early-stage research, developing synthetic routes, or planning larger-scale production, having a dependable source for intermediates like CAS: 1201186-54-0 is paramount. We encourage you to connect with us to learn more about the specific applications and to inquire about purchasing options for this important chemical compound.