For chemists engaged in intricate organic synthesis, a deep understanding of chemical intermediates is fundamental. 2-Chloro-5-methyl-3-nitropyridine (CAS: 23056-40-8) is a compound that offers a unique profile, making it highly sought after in both laboratory research and industrial chemical production. This article explores its key chemical characteristics and synthesis applications, providing valuable insights for scientists and formulators.

Chemical Properties and Structure

The compound’s structure, C6H5ClN2O2, features a pyridine ring substituted with a chlorine atom, a methyl group, and a nitro group. This arrangement dictates its chemical behavior and utility:

  • Molecular Weight: Approximately 172.57 g/mol.
  • Appearance: Typically presented as a light yellow powder.
  • Melting Point: Ranges between 46-50°C, indicating it is a solid at standard room temperatures.
  • Boiling Point: Approximately 290.8°C, signifying its thermal stability under moderate conditions.
  • Purity: High purity grades, often ≥98.0% (GC), are readily available from manufacturers, crucial for sensitive synthesis reactions.
  • Solubility: Information on solubility in common solvents is vital for experimental design, though specific data might vary.

Applications in Synthesis

The strategic placement of functional groups on the pyridine ring of 2-Chloro-5-methyl-3-nitropyridine makes it a versatile intermediate. Its primary uses include:

  • As a Pharmaceutical Intermediate: It is extensively used in the synthesis of pharmaceutical compounds, particularly in creating molecules with heterocyclic cores that are critical for drug efficacy. Researchers often seek to buy 2-Chloro-5-methyl-3-nitropyridine for its role in developing potential anti-inflammatory, antimicrobial, and other therapeutic agents.
  • As an Agrochemical Intermediate: In the agrochemical industry, it is employed in the synthesis of herbicides and pesticides. Its structure can be modified to create compounds that offer targeted pest control and improved crop yields. Professionals looking to purchase 2-Chloro-5-methyl-3-nitropyridine for these applications benefit from its reactivity.

Sourcing and Collaboration

For those requiring this compound, locating a dependable 2-Chloro-5-methyl-3-nitropyridine supplier is key. When making a purchase decision, considering factors like the supplier’s manufacturing capabilities, quality control processes, and ability to provide technical documentation is essential. Many organizations actively look for competitive 2-Chloro-5-methyl-3-nitropyridine prices from reliable manufacturers, particularly those based in China, to manage costs effectively.

Understanding the chemical profile and application potential of 2-Chloro-5-methyl-3-nitropyridine empowers chemists and procurement specialists to make informed decisions, driving successful outcomes in their research and production endeavors.