For chemists and R&D professionals engaged in synthetic organic chemistry, a thorough understanding of a chemical intermediate's profile is fundamental to its successful application. 2-Chloro-5-nitropyridine (CAS 4548-45-2) is a pyridine derivative that garners significant attention due to its utility in crafting complex molecules for the pharmaceutical and agrochemical industries. As a dedicated manufacturer and supplier in China, providing accurate chemical data is central to our service. If you intend to buy this compound, familiarizing yourself with its properties is crucial.

2-Chloro-5-nitropyridine, with the molecular formula C5H3ClN2O2 and a molecular weight of 158.54 g/mol, presents as a white to light yellow crystalline solid. This physical characteristic is a primary indicator of its purity and handling suitability. Its melting point, commonly reported between 106-110 °C, signifies its solid state under ambient conditions, which simplifies storage and transportation. The boiling point, approximately 256.6 °C at 760 mmHg, indicates its relative stability at elevated temperatures, although specific reaction conditions should always be carefully controlled.

The chemical reactivity of 2-Chloro-5-nitropyridine stems from the interplay of the electron-withdrawing nitro group and the electronegative chlorine atom on the pyridine ring. This makes the compound susceptible to nucleophilic aromatic substitution, a key reaction pathway for introducing other functional groups. Furthermore, the nitro group can be reduced to an amine, opening up further synthetic possibilities. These chemical attributes are what make it an invaluable intermediate for creating a wide range of target molecules, from drug candidates to specialized agrochemicals. For those needing to purchase this intermediate, understanding these reaction pathways helps in planning synthetic routes.

When considering sourcing this vital intermediate, working with a reputable supplier in China ensures access to reliable data and consistent product quality. Our commitment as a manufacturer means we meticulously control the synthesis process to achieve high purity (≥98.0%) and a stable crystalline form. This attention to detail is critical for synthesis experts who rely on predictable chemical behavior. By offering competitive prices and maintaining a robust supply chain, we support your research and production needs, ensuring you have access to the high-quality 2-Chloro-5-nitropyridine required for your demanding applications.