The Chemical Profile of 2-Chloromethyl-3,4-dimethoxypyridinium Chloride: Properties and Uses
Understanding the intrinsic properties of a chemical compound is fundamental for its effective application in manufacturing. 2-Chloromethyl-3,4-dimethoxypyridinium chloride (CAS 72830-09-2) is a compound that has garnered significant attention within the pharmaceutical industry, primarily for its role as a key intermediate. This article explores its chemical profile, physical characteristics, and primary applications.
Chemically, 2-Chloromethyl-3,4-dimethoxypyridinium chloride is a pyridine derivative with the molecular formula C8H11Cl2NO2 and a molecular weight of approximately 224.08 g/mol. Its IUPAC name is 2-(chloromethyl)-3,4-dimethoxypyridine;hydrochloride. The compound is typically presented as a white needle crystal, indicating a crystalline solid form. Key physical properties often documented include a melting point with decomposition (around 155 °C) and solubility characteristics, such as being soluble in water and slightly soluble in chloroform and methanol upon heating.
The primary application driving the demand for 2-Chloromethyl-3,4-dimethoxypyridinium chloride is its indispensable function as a precursor in the synthesis of pantoprazole sodium salt. Pantoprazole is a widely used medication for managing acid-related disorders, and the efficient synthesis of this API relies heavily on the quality and availability of this intermediate. Beyond this specific application, its chemical structure also makes it a valuable building block in research and development for other organic syntheses requiring similar pyridine motifs.
For pharmaceutical companies, sourcing this intermediate requires attention to detail regarding its specifications. A high assay purity, typically 98% or higher, is crucial for ensuring the success of subsequent synthesis steps and the purity of the final API. Manufacturers who can provide consistent quality, along with adherence to international standards and comprehensive documentation, are highly sought after. Whether you are looking to buy in bulk or require samples for laboratory testing, partnering with a reputable supplier or manufacturer that specializes in fine chemicals and pharmaceutical intermediates is key to successful procurement and production.
Perspectives & Insights
Chem Catalyst Pro
“A high assay purity, typically 98% or higher, is crucial for ensuring the success of subsequent synthesis steps and the purity of the final API.”
Agile Thinker 7
“Manufacturers who can provide consistent quality, along with adherence to international standards and comprehensive documentation, are highly sought after.”
Logic Spark 24
“Whether you are looking to buy in bulk or require samples for laboratory testing, partnering with a reputable supplier or manufacturer that specializes in fine chemicals and pharmaceutical intermediates is key to successful procurement and production.”