The synthesis of complex pharmaceutical APIs often relies on specialized chemical intermediates that possess specific properties and purity levels. For Pregabalin, a drug widely prescribed for neurological conditions, one such crucial intermediate is 3-Carbamoylmethy-5-methylhexanoic Acid (CAS 181289-15-6). Understanding its chemical profile is key for manufacturers aiming for efficient and high-quality production.

Chemical Identity and Properties

3-Carbamoylmethy-5-methylhexanoic Acid, with the molecular formula C9H17NO3 and a molecular weight of approximately 187.24 g/mol, is characterized by its functional groups: a carboxylic acid and a primary amide. Its physical appearance is typically a white to off-white powder. The compound's melting point is reported in the range of 106-108°C, indicating its solid state under standard conditions. While solubility data can vary, it is generally noted to have slight solubility in solvents like DMSO, methanol, and water.

Synthesis and Manufacturing Insights

The production of 3-Carbamoylmethy-5-methylhexanoic Acid often involves multi-step organic synthesis, starting from readily available raw materials. Common synthesis routes may involve the reaction of 3-isobutylglutaric anhydride with ammonia, followed by cyclization and subsequent hydrolysis or amidation steps. As a leading manufacturer in China, our processes are optimized for yield, purity, and cost-effectiveness, ensuring we can supply this intermediate reliably.

When seeking to buy this chemical, looking for manufacturers who can provide detailed analytical data, such as Nuclear Magnetic Resonance (NMR) and High-Performance Liquid Chromatography (HPLC) reports, is advisable. These reports confirm the compound's identity and purity, which are critical for pharmaceutical applications. We, as a committed supplier, ensure that our product meets rigorous quality standards, often exceeding 98% purity.

Application as a Pregabalin Intermediate

The primary application of 3-Carbamoylmethy-5-methylhexanoic Acid is its role as a direct precursor in the synthesis of Pregabalin. Its specific molecular structure facilitates the conversion into the active drug compound. For API manufacturers, securing a consistent and cost-competitive supply of this intermediate from a reliable manufacturer is paramount for maintaining production efficiency and controlling costs. We offer competitive price points for bulk purchases and are ready to discuss your specific needs.

If your research or production involves Pregabalin synthesis, exploring your sourcing options for 3-Carbamoylmethy-5-methylhexanoic Acid is essential. We invite you to purchase from us and benefit from our commitment to quality and service. Contact us to get a quote and learn more about how our expertise can support your pharmaceutical chemical needs.