The Chemical Profile of 4-(2-Methoxyethyl)phenol: An Essential Component for Metoprolol Synthesis
The intricate process of synthesizing pharmaceutical compounds relies heavily on the precise nature of chemical intermediates. For Metoprolol, a widely used beta-blocker, 4-(2-Methoxyethyl)phenol is a cornerstone intermediate. Ningbo Inno Pharmchem Co., Ltd. focuses on understanding the detailed chemical profile of such compounds to ensure optimal utilization in pharmaceutical manufacturing. This includes examining its molecular formula, weight, and physical properties, all of which are critical for successful Metoprolol intermediate manufacturing.
With the molecular formula C9H12O2 and a molecular weight of 152.19 g/mol, 4-(2-Methoxyethyl)phenol possesses a specific structure that lends itself to the complex organic synthesis required for Metoprolol. The IUPAC name, 4-(2-methoxyethyl)phenol, and its various synonyms, such as P-(2-methoxyethyl)phenol and Metoprolol Impurity B, underscore its identity and applications. The CAS number, 56718-71-9, is the unique identifier that links this chemical to global databases and regulatory listings, crucial for its traceability and use in Metoprolol synthesis.
The physical characteristics of 4-(2-Methoxyethyl)phenol are also noteworthy for those engaged in pharmaceutical synthesis. Typically appearing as a white to off-white solid, its melting point range of 42-45°C provides a key specification for quality control. This parameter is vital for ensuring the compound's integrity during storage and subsequent reactions in the Metoprolol manufacturing process. Moreover, its solubility in certain solvents, while not explicitly detailed for industrial use here, hints at the handling considerations in a laboratory or manufacturing setting.
Beyond its direct role in creating Metoprolol, 4-(2-Methoxyethyl)phenol also serves as a reference standard for identifying and quantifying Metoprolol impurities. This analytical application is indispensable for ensuring the purity and safety of the final drug product. The meticulous study of Metoprolol Impurity B, for instance, relies on the availability of pure 4-(2-Methoxyethyl)phenol. Companies engaged in Metoprolol intermediate manufacturing must ensure their product meets the purity levels required for both synthesis and analytical reference.
Ningbo Inno Pharmchem Co., Ltd. is committed to providing chemical intermediates that meet rigorous standards. By understanding and supplying compounds like 4-(2-Methoxyethyl)phenol with clarity regarding their chemical profile and applications, we aim to support the pharmaceutical industry's pursuit of high-quality, safe, and effective medicines. The reliable sourcing of this Metoprolol intermediate is fundamental to building a robust pharmaceutical supply chain.
Perspectives & Insights
Silicon Analyst 88
“Beyond its direct role in creating Metoprolol, 4-(2-Methoxyethyl)phenol also serves as a reference standard for identifying and quantifying Metoprolol impurities.”
Quantum Seeker Pro
“This analytical application is indispensable for ensuring the purity and safety of the final drug product.”
Bio Reader 7
“The meticulous study of Metoprolol Impurity B, for instance, relies on the availability of pure 4-(2-Methoxyethyl)phenol.”