For professionals in pharmaceutical research and development, a thorough understanding of the chemical and physical properties of key intermediates is essential for successful project outcomes. 4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile, a critical intermediate for the synthesis of the anti-cancer drug Gefitinib, boasts a specific profile that makes it valuable in complex organic synthesis.

This compound, identified by CAS 675126-26-8, presents as a yellow powder, a common physical characteristic for many organic intermediates. Its chemical purity is generally specified at ≥98.0%, a crucial metric for its application in API manufacturing. The molecular formula is C15H19N3O5, giving it a molecular weight of 321.328. These details are fundamental for stoichiometric calculations and reaction planning.

Key physical properties further define its handling and processing. With a density of approximately 1.3 g/cm³ and a high boiling point of around 522.3°C, the compound exhibits stability under various laboratory conditions. Its chemical structure, featuring a nitro group, a nitrile group, a methoxy ether, and a morpholine moiety connected by a propoxy linker, allows for diverse chemical transformations. For instance, the nitro group can be reduced to an amine, a common step in synthesizing quinazoline-based drugs like Gefitinib.

When considering where to buy this intermediate, the emphasis should be on manufacturers that can provide detailed specifications and a consistent product. For those looking to purchase 4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile, understanding its reactivity and stability is as important as securing a reliable supply. Its role as an impurity or precursor in Gefitinib production highlights the need for stringent quality control from the manufacturer.

We, as a dedicated manufacturer and supplier, offer this vital pharmaceutical intermediate, ensuring it meets the high standards demanded by the R&D and manufacturing sectors. By providing comprehensive product information and guaranteeing purity and bulk availability, we support your critical drug synthesis projects. Investing in high-quality chemical intermediates is an investment in the efficacy and regulatory compliance of your final pharmaceutical product. Contact us today to learn more about how our 4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile can support your development pipeline.