Understanding the detailed chemical profile of a compound is fundamental for anyone looking to buy 4-methylphenylacetic acid (CAS 622-47-9). This white crystalline powder, also known as 4-tolylacetic acid, is a significant fine chemical intermediate with applications spanning pharmaceuticals and organic synthesis. For chemists, researchers, and procurement specialists, grasping its physical properties, reactivity, and safety aspects ensures optimal utilization and safe handling. This overview aims to provide essential information about the chemical profile of 4-Methylphenylacetic acid.

Chemical Structure and Nomenclature

4-Methylphenylacetic acid possesses the molecular formula C9H10O2 and a molecular weight of 150.17 g/mol. Its structure features a phenylacetic acid core with a methyl group attached at the para (4) position of the benzene ring. This structural characteristic is key to its reactivity and applications. Common synonyms include 4-tolylacetic acid, p-tolylacetic acid, and p-methylbenzeneacetic acid, with CAS number 622-47-9 serving as its universal identifier.

Physical and Chemical Properties

As a fine crystalline powder, 4-Methylphenylacetic acid typically presents as white. Key physical properties reported include:

  • Melting Point: Approximately 88-92 °C. This relatively low melting point indicates it's a solid at room temperature and facilitates certain processing methods.
  • Boiling Point: Around 265-267 °C, indicating good thermal stability for many reactions.
  • Solubility: Soluble in methanol and other organic solvents, which is crucial for its use in solution-based reactions and purifications.
  • pKa: Approximately 4.370 at 25°C, signifying its acidic nature as a carboxylic acid.

These properties make it amenable to various chemical transformations, typical for carboxylic acids and substituted aromatic compounds. A reliable manufacturer will provide a detailed Certificate of Analysis (CoA) confirming these specifications for each batch.

Safety and Handling Precautions

According to GHS classifications, 4-Methylphenylacetic acid is typically labeled as an irritant. Hazard statements often include H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Precautionary statements emphasize wearing protective gear (gloves, eye protection, suitable respiratory protection) and ensuring adequate ventilation. Always consult the Safety Data Sheet (SDS) provided by your supplier for comprehensive safety guidance. When you buy 4-methylphenylacetic acid, ensure your team is trained on its proper handling.

Applications in Synthesis and Research

The chemical reactivity of 4-Methylphenylacetic acid makes it a valuable intermediate. It is used in:

  • Pharmaceutical Synthesis: As a building block for APIs, contributing specific structural elements to drug molecules.
  • Organic Synthesis: In the preparation of various organic compounds, acting as a precursor for amines and other functional groups.
  • Research and Development: For exploring new chemical reactions and discovering novel compounds.

For those seeking to purchase 4-methylphenylacetic acid, understanding these properties helps in selecting the most appropriate CAS 622-47-9 manufacturer that can guarantee the necessary purity and handling information.

We offer high-purity 4-Methylphenylacetic acid, backed by rigorous quality control and detailed technical documentation. As a leading Chinese manufacturer and supplier, we are ready to support your research and production needs. Contact us today to get a quote and ensure you are sourcing this essential chemical from a reliable partner.