The Chemical Profile of 5-Fluoroindole: Properties and Applications
Understanding the fundamental chemical properties of an intermediate like 5-Fluoroindole (CAS 399-52-0) is crucial for its effective utilization in various synthetic processes. This fluorinated indole derivative offers a unique combination of physical and chemical characteristics that make it valuable across several industries. As a leading supplier and manufacturer, we provide detailed information to ensure you can leverage its full potential in your applications.
5-Fluoroindole typically presents as a white to off-white powder, a common and easily handled form for chemical reagents. Its melting point is generally reported in the range of 44-48°C, indicating a relatively low melting solid at room temperature. The boiling point is considerably higher, around 258°C at atmospheric pressure (760 mmHg), suggesting good thermal stability for many reaction conditions. These physical attributes, combined with its chemical structure, define its suitability for diverse synthetic pathways.
The chemical reactivity of 5-Fluoroindole makes it an excellent intermediate for organic synthesis. The indole nucleus is a foundational structure in many natural products and pharmaceuticals, and the fluorine atom at the 5-position offers a site for further functionalization or can influence the electronic properties of the resulting molecules. This has led to its application in the synthesis of various APIs, where fluorine incorporation is a strategic approach to enhance drug efficacy and bioavailability. Furthermore, its use in preparing polyindoles highlights its utility in materials science, particularly for conductive polymers and optoelectronic devices.
As a dedicated manufacturer and supplier of 5-Fluoroindole, we ensure our product meets the high standards required for these applications. Whether you are looking to buy 5-Fluoroindole for pharmaceutical research, materials development, or general organic synthesis, we are your reliable partner. Contact us to learn more about its detailed specifications and to secure a competitive price for this essential chemical intermediate.
Perspectives & Insights
Silicon Analyst 88
“5-Fluoroindole typically presents as a white to off-white powder, a common and easily handled form for chemical reagents.”
Quantum Seeker Pro
“Its melting point is generally reported in the range of 44-48°C, indicating a relatively low melting solid at room temperature.”
Bio Reader 7
“The boiling point is considerably higher, around 258°C at atmospheric pressure (760 mmHg), suggesting good thermal stability for many reaction conditions.”