Understanding the fundamental chemical profile of an intermediate is crucial for effective utilization in synthesis and formulation. 8-Bromo-3-methylxanthine (CAS 93703-24-3) is a compound of significant interest, particularly in the pharmaceutical industry, due to its role as a key precursor in the synthesis of important APIs. This article provides an in-depth look at its chemical properties, structure, and principal applications, serving as a resource for R&D scientists and procurement specialists.

Chemically, 8-Bromo-3-methylxanthine belongs to the xanthine family, a class of purine derivatives found in various natural sources and synthesized for medicinal purposes. Its molecular formula is C6H5BrN4O2, with a molecular weight of 245.03 g/mol. Physically, it typically presents as a white to almost white crystalline powder. The compound is characterized by a high melting point, usually exceeding 300°C, which reflects its stable crystalline structure. The presence of the bromine atom at the 8-position is a key feature, providing a reactive handle for subsequent chemical transformations.

The primary application of 8-Bromo-3-methylxanthine lies in its function as a pharmaceutical intermediate. It is notably employed in the synthesis of Linagliptin, a potent and selective DPP-4 inhibitor used in the treatment of type 2 diabetes mellitus. The bromine atom allows for various cross-coupling reactions, such as palladium-catalyzed couplings, which are essential for building the complex molecular architecture required for API efficacy. This makes it a valuable starting material for pharmaceutical research and large-scale production.

For those looking to buy 8-Bromo-3-methylxanthine, understanding its reactivity is key to successful synthesis. Its chemical stability, coupled with the strategic placement of the bromine atom, makes it an ideal intermediate for many organic reactions. Sourcing from a reputable manufacturer is vital to ensure consistent purity (often greater than 98% by HPLC) and quality, which directly impacts the efficiency and outcome of downstream synthesis. We are a premier manufacturer and supplier, dedicated to providing high-quality 8-Bromo-3-methylxanthine to support your critical projects.

In conclusion, the chemical profile of 8-Bromo-3-methylxanthine highlights its importance as a versatile and critical intermediate. Its specific properties make it an indispensable component in the synthesis of vital pharmaceuticals. We encourage researchers and procurement professionals to consider our offerings for high-purity 8-Bromo-3-methylxanthine and to request a quote for your supply needs, ensuring the quality and success of your synthetic endeavors.