Understanding the detailed chemical profile of pharmaceutical impurities is fundamental for researchers and manufacturers. Celecoxib Impurity B, identified by CAS number 331943-04-5, is a critical compound for those working with the widely used COX-2 inhibitor, Celecoxib. This article provides an overview of its key chemical properties and essential applications within the pharmaceutical industry.

Chemical Identity and Properties:

  • Chemical Name: N-De(4-sulfonaMidophenyl)-N'-(4-sulfonaMidophenyl) Celecoxib
  • CAS Number: 331943-04-5
  • Molecular Formula: C17H14F3N3O2S
  • Molecular Weight: Approximately 381.37 g/mol
  • Appearance: Typically described as an Off-White Solid.

The molecular structure of Celecoxib Impurity B is closely related to Celecoxib, making it a significant isomeric impurity. This structural similarity is often the reason it retains some biological activity, specifically selective inhibition of COX-2, which is a key characteristic to monitor in pharmaceutical development.

Primary Applications:

The principal use of Celecoxib Impurity B is as a reference standard in the pharmaceutical sector. Its applications include:

  • Analytical Testing: Used in High-Performance Liquid Chromatography (HPLC) and other analytical techniques to identify and quantify its presence in Celecoxib samples.
  • Quality Control (QC): Essential for pharmaceutical manufacturers to ensure their products meet strict purity specifications set by regulatory bodies.
  • Research and Development (R&D): Aids in understanding the metabolic pathways and degradation profiles of Celecoxib, contributing to drug safety assessments.
  • Method Development: Serves as a benchmark for developing new and improving existing analytical methods for impurity detection.

For researchers and procurement specialists seeking reliable sources for this compound, NINGBO INNO PHARMCHEM CO.,LTD. is a reputable manufacturer and supplier in China. We provide high-purity Celecoxib Impurity B, essential for critical R&D and QC applications. We encourage you to buy Celecoxib Impurity B from us to ensure the quality and integrity of your pharmaceutical research. Contact our sales team for current pricing and availability to purchase this vital chemical.