Diethyl Dipropylmalonate, identified by CAS number 6065-63-0, is a chemical compound that holds significant value in various industrial applications, most notably as an intermediate in pharmaceutical synthesis. As a specialized manufacturer of Diethyl Dipropylmalonate in China, we are committed to providing detailed insights into the properties and synthesis of this crucial chemical.

Chemical Properties and Specifications: Diethyl Dipropylmalonate (C13H24O4) is an organic ester with a molecular weight of 244.33 g/mol. It typically presents as a light yellow oil at room temperature. Key physical and chemical properties include a boiling point of approximately 129-131 °C at 12 mmHg, a density around 0.96 g/mL, and a refractive index of 1.4270-1.4290. It exhibits slight solubility in chloroform and methanol. These precise specifications are vital for its effective use in synthesis and formulation.

Primary Application: Valproic Acid Synthesis: The most prominent use of Diethyl Dipropylmalonate is as a key intermediate in the preparation of Valproic Acid. This anticonvulsant medication is synthesized through a process that involves the hydrolysis and decarboxylation of Diethyl Dipropylmalonate. The purity and quality of the Diethyl Dipropylmalonate directly influence the efficacy and safety of the final pharmaceutical product. For those looking to buy Diethyl Dipropylmalonate for this purpose, partnering with a reliable supplier is paramount.

Broader Industrial Uses: Beyond pharmaceuticals, Diethyl Dipropylmalonate is a versatile reagent in general organic synthesis. Its ester functionalities and the presence of two propyl groups allow for its use as a building block in the creation of various fine chemicals and specialty compounds. Researchers and formulators utilize its reactive nature for alkylation, condensation, and other synthetic transformations to develop novel materials and products.

Synthesis Routes: While specific proprietary synthesis methods vary among manufacturers, the production of Diethyl Dipropylmalonate typically involves the reaction of diethyl malonate with a propyl halide (like 1-bromopropane or 1-iodopropane) in the presence of a base, such as sodium ethoxide. The efficiency and selectivity of these reactions are critical for achieving high yields and purity. As a dedicated manufacturer, we employ optimized synthesis strategies to ensure the consistent quality of our Diethyl Dipropylmalonate.

Sourcing and Value: For businesses seeking to source this intermediate, understanding the price of Diethyl Dipropylmalonate and ensuring consistent supply is crucial. Our position as a leading supplier in China allows us to offer high-quality Diethyl Dipropylmalonate at competitive prices. We are committed to supporting our clients with both product excellence and efficient logistics, making us a trusted partner for your chemical needs.

In summary, Diethyl Dipropylmalonate (CAS 6065-63-0) is a significant chemical intermediate with critical applications in the pharmaceutical and fine chemical sectors. We invite you to explore our offerings and discover how our commitment to quality and competitive pricing can benefit your procurement needs.