Diethyl Tartrate (2S,3S), CAS 13811-71-7, is a chemical compound renowned for its role as a chiral building block. Its specific stereochemical configuration dictates its utility in a myriad of synthetic applications, particularly within the pharmaceutical and fine chemical sectors. Understanding its chemical profile, including physical properties and common synthesis methods, is essential for any professional working with this material.

The physical characteristics of Diethyl Tartrate (2S,3S) are notable: it is typically described as a viscous liquid, clear and colorless to a pale yellow hue. Key properties often cited include a density of around 1.205 g/mL at 20 °C and a refractive index (n20/D) of approximately 1.446. While its melting point is low (around 17 °C), its boiling point is significantly higher, often reported at 162 °C under 19 mmHg pressure. Its solubility in water is limited, but it readily mixes with common organic solvents like ethanol and diethyl ether.

The synthesis of Diethyl Tartrate (2S,3S) typically involves the esterification of D-tartaric acid with ethanol. Various methods exist, often employing acid catalysts such as hydrochloric acid or thionyl chloride to facilitate the reaction. Purification is a critical step, often involving distillation under high vacuum or molecular distillation to achieve the high purity and optical purity required for its applications. Ensuring minimal levels of impurities like diethyl malate or diethyl fumarate is key to its performance in sensitive chemical processes.

Manufacturers in the chemical industry focus on optimizing these synthesis and purification protocols to deliver a product that meets stringent specifications. For businesses seeking to buy Diethyl Tartrate (2S,3S), partnering with suppliers who can detail their manufacturing processes and quality control measures provides assurance. Information regarding raw material sourcing, reaction conditions, and purification techniques can offer valuable insights into the reliability of the product.

As a vital chiral intermediate, Diethyl Tartrate (2S,3S) continues to be a staple in the toolkit of synthetic organic chemists. Its consistent availability at high purity from reputable manufacturers and suppliers is crucial for advancing research and development in areas requiring precise stereochemical control. The ongoing innovation in its production methods further cements its importance in the chemical supply chain.