In the realm of pharmaceutical manufacturing, a deep understanding of the chemical and physical properties of intermediates is fundamental to successful synthesis. Ethyl 3,4-Dihydroxybenzoate (CAS: 3943-89-3), also known as Ethyl Protocatechuate, is a critical intermediate with a specific profile that makes it invaluable. This article provides an overview of its key characteristics and applications, particularly relevant for R&D scientists and procurement professionals.

Ethyl 3,4-Dihydroxybenzoate is defined by its chemical formula, C9H10O4, and a molecular weight of approximately 182.17300 g/mol. Its structure contains a catechol moiety, which contributes to its reactivity and suitability as a synthetic building block. Commonly supplied as a white to pale beige crystalline powder, its physical state is stable under appropriate storage conditions. The reported melting point range of 132-134 °C is a key specification for quality control, ensuring product consistency for any 'manufacturer or supplier'.

The significance of Ethyl 3,4-Dihydroxybenzoate is predominantly its role as a crucial intermediate in the production of Erlotinib and Erlotinib Hydrochloride. These pharmaceuticals are vital in treating specific forms of cancer, such as non-small cell lung cancer. The synthesis process demands intermediates with high purity, typically above 99%, to ensure the efficacy and safety of the final drug product. Therefore, when seeking to 'buy' this compound, verifying its specifications from a reliable 'pharmaceutical intermediate supplier' is essential.

Beyond its primary use, the chemical structure of Ethyl 3,4-Dihydroxybenzoate suggests potential antioxidant properties due to its phenolic hydroxyl groups, although its main commercial value remains in its synthetic utility. For researchers, understanding these properties can open avenues for further exploration in medicinal chemistry.

Procurement managers looking for a 'CAS 3943-89-3 manufacturer' should prioritize those with robust quality management systems. A competitive 'price for Ethyl 3,4-Dihydroxybenzoate' is important, but it must be balanced against the assurance of quality, timely delivery, and comprehensive documentation, such as a Certificate of Analysis (CoA) and Material Safety Data Sheet (MSDS). The availability of bulk quantities from a trusted 'China supplier' further facilitates large-scale pharmaceutical manufacturing.

In summary, Ethyl 3,4-Dihydroxybenzoate is a compound with a well-defined chemical and physical profile, making it a critical intermediate for the pharmaceutical industry, particularly in the synthesis of Erlotinib. By focusing on sourcing from reputable manufacturers and understanding its properties, companies can ensure the quality and efficiency of their drug production processes.