The Chemical Profile of Ethyl Isonicotinate N-Oxide: Properties and Reactivity
Ethyl Isonicotinate N-Oxide (CAS 14906-37-7) is a compound of significant interest in the chemical industry due to its unique structural features and versatile reactivity. Understanding its chemical profile is key for optimizing its use in various synthesis applications. NINGBO INNO PHARMCHEM CO.,LTD., a distinguished manufacturer in China, offers this fine chemical, providing essential insights into its properties and how they translate to practical applications.
The compound's molecular formula, C8H9NO3, with a molecular weight of 167.16 g/mol, describes a pyridine derivative featuring an N-oxide group and an ethyl ester substituent. This N-oxide functionality profoundly influences the electron distribution within the pyridine ring, activating specific positions for chemical attack and altering its overall reactivity compared to its non-oxidized counterparts. The physical appearance is typically an off-white to light yellow crystal, with a melting point around 68-70 °C, indicating a stable solid form conducive to handling and storage. Its solubility in organic solvents like dichloromethane and ethanol further enhances its utility in various reaction media.
The reactivity of Ethyl Isonicotinate N-Oxide is a cornerstone of its value in organic synthesis. It is known to participate in nucleophilic addition reactions and can serve as an acyl donor in enzymatic processes, as seen in the synthesis of certain pharmaceuticals. The presence of the N-oxide group can also facilitate electrophilic substitution reactions at positions adjacent to the nitrogen atom, offering pathways not readily available with simple pyridines. This inherent versatility allows chemists to buy this compound as a strategic intermediate for building complex molecular architectures.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing detailed technical information on our products, including Ethyl Isonicotinate N-Oxide. Our expertise as a manufacturer in China ensures that the chemical properties and purity levels are consistently maintained, making it a reliable choice for demanding synthesis projects. By understanding the chemical profile and reactivity of this compound, researchers and manufacturers can better leverage its potential to drive innovation and achieve superior results in their chemical endeavors.
Perspectives & Insights
Agile Reader One
“The presence of the N-oxide group can also facilitate electrophilic substitution reactions at positions adjacent to the nitrogen atom, offering pathways not readily available with simple pyridines.”
Logic Vision Labs
“This inherent versatility allows chemists to buy this compound as a strategic intermediate for building complex molecular architectures.”
Molecule Origin 88
“is committed to providing detailed technical information on our products, including Ethyl Isonicotinate N-Oxide.”