The Chemical Profile of Irbesartan: Purity, Properties, and Applications
Understanding the chemical nuances of pharmaceutical intermediates is fundamental for researchers and manufacturers aiming for excellence in drug development. Irbesartan, with its CAS number 138402-11-6, is a prime example of such a crucial intermediate, underpinning the production of medications vital for cardiovascular health and kidney protection.
The chemical identity of Irbesartan is defined by its molecular formula, C25H28N6O, and a molecular weight of 428.529. Crucially, it is typically supplied as a white powder, a visual confirmation of its quality. For pharmaceutical applications, the purity of Irbesartan is a non-negotiable specification, with manufacturers striving for a minimum of 99%. This high level of purity is essential to prevent unwanted side reactions during synthesis and to ensure the safety and efficacy of the final drug product. The melting point, often cited as 180-181°C, serves as another key indicator of its chemical integrity.
The primary application of Irbesartan is its function as a pharmaceutical intermediate in the synthesis of angiotensin II receptor antagonists (ARBs). These drugs are widely prescribed for the treatment of hypertension (high blood pressure) and are also instrumental in managing diabetic nephropathy—kidney disease that can develop in individuals with diabetes. By blocking the action of angiotensin II, Irbesartan helps to relax blood vessels, thereby lowering blood pressure and protecting the delicate kidney tissues.
For businesses looking to buy Irbesartan, it is important to consider the source. Reputable manufacturers and suppliers, particularly those based in China, offer this intermediate with a strong emphasis on quality control. When you engage with an Irbesartan supplier China, verify their adherence to strict manufacturing protocols and their ability to provide consistent product batches. The Irbesartan CAS 138402-11-6 price will naturally reflect its purity and the manufacturing standards employed.
As a vital component in the pharmaceutical supply chain, sourcing Irbesartan requires diligence. Identifying a dependable Irbesartan manufacturer that prioritizes quality assurance and offers competitive pricing ensures that your R&D or production processes are supported by a reliable foundation. Whether for large-scale manufacturing or niche research projects, understanding the chemical profile of Irbesartan is key to making informed sourcing decisions.
In essence, Irbesartan is more than just a chemical compound; it's a critical building block for medicines that improve and save lives. Its precise chemical characteristics, combined with a reliable supply from manufacturers committed to high purity, make it an indispensable intermediate in the modern pharmaceutical industry.
Perspectives & Insights
Agile Reader One
“This high level of purity is essential to prevent unwanted side reactions during synthesis and to ensure the safety and efficacy of the final drug product.”
Logic Vision Labs
“The melting point, often cited as 180-181°C, serves as another key indicator of its chemical integrity.”
Molecule Origin 88
“The primary application of Irbesartan is its function as a pharmaceutical intermediate in the synthesis of angiotensin II receptor antagonists (ARBs).”